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LineagePulse

Bioc removed

Differential expression analysis and model fitting for single-cell RNA-seq data

v1.22.0 · Artistic-2.0

Release Lineage

Entered 3.7 · May 1, 2018

Removed after 3.18 · Oct 25, 2023

1.0 In 12 of 49 releases 3.23

Description

LineagePulse is a differential expression and expression model fitting package tailored to single-cell RNA-seq data (scRNA-seq). LineagePulse accounts for batch effects, drop-out and variable sequencing depth. One can use LineagePulse to perform longitudinal differential expression analysis across pseudotime as a continuous coordinate or between discrete groups of cells (e.g. pre-defined clusters or experimental conditions). Expression model fits can be directly extracted from LineagePulse.

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