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IgGeneUsage

Bioc current

Differential gene usage in immune repertoires

v1.26.0 · software · MIT + file LICENSE
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Release Lineage

Entered 3.10 · Oct 30, 2019

Current · Requires R 4.6

1.0 In 14 of 49 releases 3.23

Description

Detection of biases in the usage of immunoglobulin (Ig) genes is an important task in immune repertoire profiling. IgGeneUsage detects aberrant Ig gene usage between biological conditions using a probabilistic model which is analyzed computationally by Bayes inference. With this IgGeneUsage also avoids some common problems related to the current practice of null-hypothesis significance testing.

Code

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Topics

Software › BiologicalQuestion › DifferentialExpression
Software › StatisticalMethod › Regression
Software › ResearchField › Genetics
Software › StatisticalMethod › Bayesian
Software › ResearchField › BiomedicalInformatics
Software › ResearchField › Immunology › ImmunoOncology
Software › ResearchField › MathematicalBiology

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