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DominoEffect

1.32.0Bioconductor

Identification and Annotation of Protein Hotspot Residues

Record of Bioconductor 3.23Compare with 3.22LicencesSBOM

BiocManager::install("DominoEffect")
Distinct IPs a month, method
625Rank 1,318 in its category
Bioconductor releases
17since 2018
Advisories, method
None publishedfor Bioconductor

The functions support identification and annotation of hotspot residues in proteins. These are individual amino acids that accumulate mutations at a much higher rate than their surrounding regions.

Maintainer
Marija Buljan
Licence
GPL (>= 3)
Last updated
28 Apr 2026
First release
Bioconductor 3.7, 1 May 2018

Compare with another package

More details
Releases
17 of 49 Bioconductor releases
Category
software
Needs R
>= 3.5
LazyData
true
RoxygenNote
6.0.1
biocViews (5)
Cite

Package

Run in R for the authors' entry:

citation("DominoEffect")

The package provides a citation file, so citation() returns the authors' own entry.

It points to 10.15252/msb.20177974.

R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA
Balamuta, J. J. (2026). R Observatory: Metrics for DominoEffect version 1.32.0 [Data set]. HJJB, LLC. Data release v2026-10-26. https://doi.org/10.5281/zenodo.21843040
About

From data release v2026-10-26, which the citation names so these numbers can be found later.

Release 3.23: OK 22 Oct 2026

  • kunpeng2, Install

    Install on the build machine kunpeng2. Bioconductor release 3.23.

    OK

    Version built
    1.32.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    22 Oct 2026
  • kunpeng2, Build

    Build on the build machine kunpeng2. Bioconductor release 3.23.

    OK

    Version built
    1.32.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    22 Oct 2026
  • kunpeng2, Check

    Check on the build machine kunpeng2. Bioconductor release 3.23.

    OK

    Version built
    1.32.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    22 Oct 2026
  • nebbiolo1, Install

    Install on the build machine nebbiolo1. Bioconductor release 3.23.

    OK

    Version built
    1.32.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    22 Oct 2026
  • nebbiolo1, Build

    Build on the build machine nebbiolo1. Bioconductor release 3.23.

    OK

    Version built
    1.32.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    22 Oct 2026
  • nebbiolo1, Check

    Check on the build machine nebbiolo1. Bioconductor release 3.23.

    OK

    Version built
    1.32.0
    In this state since
    14 Oct 2026
    Last seen
    22 Oct 2026
  • 6 OK
Machines (2)
MachineInstallBuildCheck
kunpeng2OKOKOK
nebbiolo1OKOKOK
Devel 3.24: OK
  • lconway, Install

    Install on the build machine lconway. The next Bioconductor release, 3.24.

    OK

    Version built
    1.33.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • lconway, Build

    Build on the build machine lconway. The next Bioconductor release, 3.24.

    OK

    Version built
    1.33.0
    In this state since
    14 Oct 2026
    Last seen
    23 Oct 2026
  • lconway, Check

    Check on the build machine lconway. The next Bioconductor release, 3.24.

    OK

    Version built
    1.33.0
    In this state since
    21 Oct 2026
    Last seen
    23 Oct 2026
  • lconway, Build binary

    Build binary on the build machine lconway. The next Bioconductor release, 3.24.

    OK

    Version built
    1.33.0
    In this state since
    14 Oct 2026
    Last seen
    23 Oct 2026
  • nebbiolo2, Install

    Install on the build machine nebbiolo2. The next Bioconductor release, 3.24.

    OK

    Version built
    1.33.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • nebbiolo2, Build

    Build on the build machine nebbiolo2. The next Bioconductor release, 3.24.

    OK

    Version built
    1.33.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • nebbiolo2, Check

    Check on the build machine nebbiolo2. The next Bioconductor release, 3.24.

    OK

    Version built
    1.33.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • taishan, Install

    Install on the build machine taishan. The next Bioconductor release, 3.24.

    OK

    Version built
    1.33.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • taishan, Build

    Build on the build machine taishan. The next Bioconductor release, 3.24.

    OK

    Version built
    1.33.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • taishan, Check

    Check on the build machine taishan. The next Bioconductor release, 3.24.

    OK

    Version built
    1.33.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • 10 OK
MachineInstallBuildCheckBuild binary
lconwayOKOKOKOK
nebbiolo2OKOKOK
taishanOKOKOK
Built files (4)
PlatformKindFile
macOS (Intel)binaryDominoEffect_1.32.0.tgz
macOS (Apple Silicon)binaryDominoEffect_1.32.0.tgz
sourcesourceDominoEffect_1.32.0.tar.gz
WindowsbinaryDominoEffect_1.32.0.zip
Total downloads in the latest complete month
4,891It comes from Bioconductor alone. Bioconda was counted over another window, so it is not added.

Rank in category, by distinct IPs

1,318 of 3,170

Bioconductor

4,891 downloads in the latest complete month

Distinct IP addresses average 625 a month over 12 months, which is a different measure and is never added.

It is in the total. Take it out

Bioconda

70 downloads in the last 30 days

It is not added because it has no figure for the latest complete month.

This local copy has no series over time.

Compare downloads

Needs
13
Dependent packages
00 on CRAN, 0 on Bioconductor
Suggested by
0
Needs (13)
Optional extras (3)
Functions
7
Public exports
7
Lines of R code
714
Median complexity
12
Functions (7)
Size and composition

Lines by kind (1,253)

KindLinesShare
R code71457%
Tests847%
Documentation26021%
Guides19516%

Lines by language

LanguageLinesShare
R79864%
Rd26021%
Vignettes19516%

Languages are counted from file extensions.

Files
25
R functions
7
Complexity
Median
12
Mean
13
Highest
31
Median lines per function
51
About complexity

Cyclomatic complexity counts the independent paths through a function: 1 is a straight line, higher is harder to test. R functions only.

Call graph figures
R functions
7
Calls
5
Unconnected
1
Groups
1
Growth (17 releases)
Total lines by release
1,251 on 30 Apr 20181,253 on 28 Apr 2026
Release changes

Test coverage is measured for CRAN packages only. Nothing is known for Bioconductor packages, which is not the same as no coverage.

Test cases
5
Lines of tests
84
Exports named in tests
71.4%
Has tests
Yes
Test frameworks
testthat
Test lines per line of code
0.12
Exports documented
100%
Arguments documented
100%
Return value documented
100%
Help pages with examples
87.5%
Examples run in checks
85.7%
Guides (1)
Other documentation
README
No
Release notes file
Yes
Help pages
8
Lines of documentation
260
DatasetSizeColumns
DominoDataSample data20,300 × 5Ensembl_gene_id, Representative_tr, cDNA_length, Gene_name, Uniprot_id
SnpDataSample data423 × 3Chr_name, Position_on_chr, Minor_allele_freq
TestDataSample data1,820 × 8Ensembl_gene_id, Protein_residue, Original_aa, Mutated_aa, Patient_id, Genomic_coordinate and 2 more

No repository on record

Bioconductor git

R releases
  • In Bioconductor
  • Bioconductor release
ReleaseReleasedR
3.23 current29 Apr 20264.6
3.2230 Oct 20254.5
3.2116 Apr 20254.5
3.2030 Oct 20244.4
3.191 May 20244.4
3.1825 Oct 20234.3
3.1726 Apr 20234.3
3.162 Nov 20224.2
Earlier releases (9)
ReleaseReleasedR
3.1527 Apr 20224.2
3.1427 Oct 20214.1
3.1320 May 20214.1
3.1228 Oct 20204.0
3.1128 Apr 20204.0
3.1030 Oct 20193.6
3.93 May 20193.6
3.831 Oct 20183.5
3.71 May 20183.5
Entered Bioconductor
Release 3.7, 1 May 2018