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CytoMethIC

Bioc current

DNA methylation-based machine learning models

v1.8.0 · experiment · Artistic-2.0

Release Lineage

Entered 3.19 · May 1, 2024

Current · Requires R 4.6

1.0 In 5 of 49 releases 3.23

Description

This package provides model data and functions for easily using machine learning models that use data from the DNA methylome to classify cancer type and phenotype from a sample. The primary motivation for the development of this package is to abstract away the granular and accessibility-limiting code required to utilize machine learning models in R. Our package provides this abstraction for RandomForest, e1071 Support Vector, Extreme Gradient Boosting, and Tensorflow models. This is paired with an ExperimentHub component, which contains models developed for epigenetic cancer classification and predicting phenotypes. This includes CNS tumor classification, Pan-cancer classification, race prediction, cell of origin classification, and subtype classification models. The package links to our models on ExperimentHub. The package currently supports HM450, EPIC, EPICv2, MSA, and MM285.

Test coverage

Line coverage

Expression

Tests / Examples

Functions

9 4 exported

Complexity

4.6 avg / 14 max

Call network

9 nodes / 6 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

877

Files

29

Compiled share

0%

Has compiled src

No

Language breakdown

R 350 (39.9%)Tests 27 (3.1%)Docs 221 (25.2%)Vignettes 279 (31.8%)

API

Exported functions

5

Internal functions

5

Recent export changes

v3.21+2 cmi_deconvolution, cmi_deconvolution2
v3.19+3 cmi_checkVersion, cmi_models, cmi_predict

Testing & CI

Has tests

Yes

Test-to-code ratio

0.08

testthat edition

CI present

No

CI type

[]

PR gated

No

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

4.4.0

System requirements

C++ standard

License

Artistic-2.0

License flags

SPDX valid, OSI approved

History

Versions

5

First release

2024-04-30

Latest release

2026-04-28

Avg cadence

182 days

Cold removal rate

Dep drift

1

LOC over versions

v3.19: 501 LOCv3.20: 501 LOCv3.21: 877 LOCv3.22: 877 LOCv3.23: 877 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

Documentation
READMEYes · 9 wordsVignettesYes · dynamicpkgdown siteNoNEWSYes · 0% structuredCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
100%
Return-value docs
100%
References docs
0%

Topics

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("CytoMethIC")
Fanale, J., & Zhou, W. (2026). CytoMethIC: DNA methylation-based machine learning models (Version 1.8.0) [Computer software]. https://bioconductor.org/packages/CytoMethIC

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for CytoMethIC version 1.8.0 [Data set]. HJJB, LLC. Data release v2026-08-22. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-22, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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