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CARDspa

Bioc current

Spatially Informed Cell Type Deconvolution for Spatial Transcriptomics

v1.4.0 · software · GPL-3 + file LICENSE

Release Lineage

Entered 3.21 · Apr 16, 2025

Current · Requires R 4.6

1.0 In 3 of 49 releases 3.23

Description

CARD is a reference-based deconvolution method that estimates cell type composition in spatial transcriptomics based on cell type specific expression information obtained from a reference scRNA-seq data. A key feature of CARD is its ability to accommodate spatial correlation in the cell type composition across tissue locations, enabling accurate and spatially informed cell type deconvolution as well as refined spatial map construction. CARD relies on an efficient optimization algorithm for constrained maximum likelihood estimation and is scalable to spatial transcriptomics with tens of thousands of spatial locations and tens of thousands of genes.

Test coverage

Line coverage

Expression

Tests / Examples

Functions

29 9 exported

Complexity

6.2 avg / 26 max

Call network

29 nodes / 18 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

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Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

4,997

Files

69

Compiled share

8.3%

Has compiled src

Yes

Language breakdown

R 2,525 (50.5%)C/C++/src 415 (8.3%)Tests 126 (2.5%)Docs 1,323 (26.5%)Vignettes 608 (12.2%)

API

Exported functions

9

Internal functions

15

Recent export changes

v3.21+9 CARD_deconvolution, CARD_imputation, CARD_refFree +6 more

Testing & CI

Has tests

Yes

Test-to-code ratio

0.05

testthat edition

CI present

No

CI type

[]

PR gated

No

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

0%

Unsafe pattern score

0

Dep constraint coverage

3.6%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

4.3.0

System requirements

C++ standard

License

GPL-3 + file LICENSE

License flags

SPDX valid, OSI approved

History

Versions

3

First release

2025-04-15

Latest release

2026-04-28

Avg cadence

189 days

Cold removal rate

Dep drift

1

LOC over versions

v3.21: 4,992 LOCv3.22: 4,997 LOCv3.23: 4,997 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

Documentation
READMEYes · 272 wordsVignettesYes · dynamicpkgdown siteNoNEWSYes · 100% structuredCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
100%
Return-value docs
100%
References docs
0%

Topics

Depended on by (1)

Bioconductor (1)

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("CARDspa")
Fu, J., & Ma, Y. (2026). CARDspa: Spatially Informed Cell Type Deconvolution for Spatial Transcriptomics (Version 1.4.0) [Computer software]. https://bioconductor.org/packages/CARDspa

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for CARDspa version 1.4.0 [Data set]. HJJB, LLC. Data release v2026-08-22. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-22, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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