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xpose4

4.7.4Package record

Diagnostics for Nonlinear Mixed-Effect Models

0packages depend
8.7Kdownloads / year
16.1%test coverage
13/13flavors OK

Overview

About

A model building aid for nonlinear mixed-effects (population) model analysis using NONMEM, facilitating data set checkout, exploration and visualization, model diagnostics, candidate covariate identification and model comparison. The methods are described in Keizer et al. (2013) doi:10.1038/psp.2013.24, and Jonsson et al. (1999) doi:10.1016/s0169-2607(98)00067-4.

Changes in 4.7.4
  • Cross-references to other R packages in documentation have been updated according to R standards.

From NEWS.md in the release

Install

Health

CRAN checks
13OK
Slowest check: 5.7 min · r-oldrel-windows-x86_64
Status changes
  • OK13 OK2026-08-04
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK13 OK2026-06-09
  • ERROR12 OK, 1 ERROR2026-06-08
  • OK14 OK2026-03-10
Advisories

none known

Documentation

In release 4.7.4
READMEYes · 382 wordsVignettesNoNEWSYes · 67% structured · mentions 4.7.4Citation fileYes · cites a publicationWebsiteYes · pkgdown
Help pages
161 (9 internal)includes a package overview page
Examples that run
58%65 run in a plain check · 47 never run
Exported functions with examples
75%
Documented parameters
96%
Return-value docs
83%
Help pages citing references
2%

Downloads

8.7K
CRAN downloads in the past year
Rank #4,328 · ~24/day · ~722/mo
Daily download trend is not available in this view yet.
64630 days
2K90 days
8.7K1 year
Compare downloads with other packages →
Also on114 r2u7 autocran95 c2d4u

Repository

38Stars
11Forks
19Open issues
1Open PRs
10Releases
260Commits
5Commit identities
pharmacometricsxposecrannonmemdiagnosticspopulation-model
License file reads as LGPL-3.0 · 260 commits · Last activity 2025-09-05 · 0% stars, 30d · Default branch at 4.7.4.9000, ahead of CRAN 4.7.4 (checked 2026-10-11) · Discussions: 2 posts
Responsiveness
How these are sampled
PRs merged (all time)
86%
Median days to close, 50 most recently updated closed issues
119
Median days to close, 50 most recently updated closed PRs
9

Stars over time

2025-05-01 · 372026-07-07 · 38
PracticesBeta

10 development-tooling and community-health practices detected across 6 families in the upstream repository

Checks run against github.com/uupharmacometrics/xpose4 on 2026-10-11.

Continuous integration (2)
GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel

Docs source (4)
README.Rmdpkgdown

GitHub Pages site last deployed 2025-09-05 · The repository has a site deploy workflow

pkgdown site last built 2025-09-03

Coverage (1)
Coverage reporting
Reproducibility and dev environment (1)
data-raw/
Show all practicesHide 2 practices
CRAN release process (1)
cran-comments.md
Lint, format, editor (1)
RStudio project
How this is detected·Detection ruleset v3 (2026-09-26)

Dependencies

Declared dependencies
7 external dependencies (excludes base and recommended)

Installing xpose4 adds 72 packages (37 with compiled code, 57 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, data.table 5.7 MB.

Depends (2)
R >= 2.2.0lattice
Imports (10)
Hmiscsurvivaldplyrtibblemethodslazyevalgamsplinesgridreadr
LinkingTo (0)
none
Suggests (1)
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Datasets

People & History

People (5)
Author, Maintainer, Copyright holder · added in 4.5.3
Author, Translator, Copyright holder
Author, Copyright holder · added in 4.5.3
Author · added in 4.5.3
Contributor · added in 4.5.3
functionality for bootstrap of GAM and SCM

Maintainer since 4.3.0 (2010)

Listed in earlier versions (2)
no longer listed · 4.3.0 to 4.5.0
Mats Karlsson
no longer listed · 4.3.0 to 4.5.0
Releases (14)

Pick two releases to compare their code metrics.

  • R
    R 4.6.0 released · 2026-04-24
  • 4.7.4Latest
    record
    2025-09-03 · current release · diff ↗
  • R
    R 4.5.0 released · 2025-04-11
  • R
    R 4.4.0 released · 2024-04-24
  • 4.7.3
    record
    2024-02-22 · diff ↗
  • R
    R 4.3.0 released · 2023-04-21
  • 4.7.2
    record
    2022-05-31 · diff ↗
  • R
    R 4.2.0 released · 2022-04-22
  • R
    R 4.1.0 released · 2021-05-18
  • unarchivedReturned to CRAN
    2020-12-18
  • 4.7.1
    record
    2020-12-18 · diff ↗
  • archivedRemoved from CRAN
    2020-12-10
    check problems were not corrected in time
  • R
    R 4.0.0 released · 2020-04-24
  • 4.7.0
    record
    2020-02-27 · diff ↗
  • R
    R 3.6.0 released · 2019-04-26
  • R
    R 3.5.0 released · 2018-04-23
Show 18 earlier eventsHide 18 earlier events
  • 4.6.1
    record
    2018-03-08 · diff ↗ ·
    added 1 export
    change.xvardef<-
  • 4.6.0
    record
    2017-06-17 · diff ↗ ·
    removed 1 export
    pattern:^[^\\.]
    added 198 exports
    Data<-, SData<-, change.cat.cont<-, change.cat.levels<-, change.dv.cat.levels<-, xlabel<-, xsubset<-, xvardef<-, Data, SData, absval.cwres.vs.cov.bw, absval.cwres.vs.pred, absval.cwres.vs.pred.by.cov, absval.dcwres.vs.cov.model.comp, absval.dipred.vs.cov.model.comp, absval.diwres.vs.cov.model.comp, absval.dpred.vs.cov.model.comp, absval.dwres.vs.cov.model.comp, absval.iwres.cwres.vs.ipred.pred, absval.iwres.vs.cov.bw, absval.iwres.vs.idv, absval.iwres.vs.ipred, absval.iwres.vs.ipred.by.cov, absval.iwres.vs.pred, absval.iwres.wres.vs.ipred.pred, absval.wres.vs.cov.bw, absval.wres.vs.idv, absval.wres.vs.pred, absval.wres.vs.pred.by.cov, add.absval and 168 more
  • R
    R 3.4.0 released · 2017-04-21
  • R
    R 3.3.0 released · 2016-05-03
  • R
    R 3.2.0 released · 2015-04-16
  • 4.5.3
    record
    2014-11-24 · diff ↗
  • 4.5.0
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    2014-05-20 · diff ↗
  • R
    R 3.1.0 released · 2014-04-10
  • 4.4.1
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    2013-08-13 · diff ↗
  • R
    R 3.0.0 released · 2013-04-03
  • 4.4.0
    record
    2012-10-17 · diff ↗
  • 4.3.5
    record
    2012-04-19 · diff ↗
  • R
    R 2.15.0 released · 2012-03-30
  • R
    R 2.14.0 released · 2011-10-31
  • R
    R 2.13.0 released · 2011-04-13
  • 4.3.2
    record
    2010-11-30 · diff ↗
  • 4.3.0
    record
    2010-10-23
  • R
    R 2.12.0 released · 2010-10-15

Package metadata

First published
2010-10-23
Total releases
14 / 16 yrs
License
LGPL (>= 3) OSI
Copyright
2009-2025 Andrew C. Hooker, E. Niclas Jonsson and Mats O. Karlsson. 2005-2008 Andrew C. Hooker, Justin J. Wilkins, Mats O. Karlsson and E. Niclas Jonsson. 1998-2004 E. Niclas Jonsson and Mats Karlsson.
Minimum R
≥ 2.2.0
Bundled data
33 KB / 1 file
Download size
608 KB
Appears in task views

Cite

Cite this package

Run in R for the authors' entry:

citation("xpose4")

The package provides a citation file, so citation() returns the authors' own entry.

It points to 10.1016/s0169-2607(98)00067-4, 10.1038/psp.2013.24.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for xpose4 version 4.7.4 [Data set]. HJJB, LLC. Data release v2026-10-18. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-18, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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