Skip to content

Computing Weighted Topological Overlaps (wTO) & Consensus wTO Network

1packages dependsuggested by 1
4.1Kdownloads / year
–test coverage
11/13flavors OK

Overview

About

Computes the Weighted Topological Overlap with positive and negative signs (wTO) networks given a data frame containing the mRNA count/ expression/ abundance per sample, and a vector containing the interested nodes of interaction (a subset of the elements of the full data frame). It also computes the cut-off threshold or p-value based on the individuals bootstrap or the values reshuffle per individual. It also allows the construction of a consensus network, based on multiple wTO networks. The package includes a visualization tool for the networks. More about the methodology can be found at doi:10.1186/s12859-018-2351-7.

Install

Health

CRAN checks
2NOTE11OK
Check messages
NOTECRAN incoming feasibilityr-devel-linux-x86_64-debian-clang, r-devel-linux-x86_64-debian-gcc
Maintainer: ‘Deisy Morselli Gysi <deisy.ccnr@gmail.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = c("Deisy", "Morselli"),
                      family = "Gysi",
                      role = c("aut", "cre"),
                      email = "deisy.ccnr@gmail.com"),
               person(given = "Andre",
                      family = "Voigt",
                      role = "aut"),
               person(given = c("Tiago", "Miranda"),
                      family = "Fragoso",
                      role = "aut"),
               person(given = "Eivind",
                      family = "Almaas",
                      role = "aut"),
               person(given = "Katja",
                      family = "Nowick.",
                      role = "aut"))
as necessary.

CRAN check page ↗

Slowest check: 1.4 min · r-oldrel-windows-x86_64
Status changes
  • NOTE11 OK, 2 NOTENow
  • NOTE12 OK, 2 NOTE2026-03-10
Advisories

none known

Documentation

In release 2.1
READMEYes · 15 wordsVignettesNoNEWSNoCitation fileYes · cites a publicationWebsitenot declared in DESCRIPTION
Help pages
17 (4 internal)
Examples that run
17%1 run in a plain check · 4 never run · 1 hold no code
Exported functions with examples
67%
Documented parameters
98%
Return-value docs
33%
Help pages citing references
6%

Downloads

4.1K
CRAN downloads in the past year
Rank #9,725 · ~11/day · ~339/mo
Daily download trend is not available in this view yet.
35130 days
1K90 days
4.1K1 year
Compare downloads with other packages →
Also on78 r2u6 autocran1.6K conda_forge59 c2d4u

Dependencies

Declared dependencies
11 external dependencies (excludes base and recommended)

Installing wTO adds 46 packages (30 with compiled code, 51 MB of source tarballs). Heaviest: stringi 11 MB, data.table 5.7 MB, bslib 5.6 MB.

Depends (0)
none
LinkingTo (0)
none
Suggests (2)
Enhances (0)
none
Reverse dependencies
1direct
0indirect
Imports 1
Suggested by 1
Depends, Imports or LinkingTo, most downloaded first
Suggests, most downloaded first

Datasets

People & History

People (from the free-text Author field) (5)

Maintainer since 1.1.0 (2017)

Releases (16)

Pick two releases to compare their code metrics.

  • R
    R 4.6.0 released · 2026-04-24
  • R
    R 4.5.0 released · 2025-04-11
  • unarchivedReturned to CRAN
    2024-07-05
  • 2.1Latest
    record
    2024-07-05 · current release · diff ↗
  • R
    R 4.4.0 released · 2024-04-24
  • archivedRemoved from CRAN
    2024-04-20
    issues were not corrected despite reminders
  • R
    R 4.3.0 released · 2023-04-21
  • 2.0.2
    record
    2023-03-22 · diff ↗
  • 2.0.1
    record
    2022-05-24 · diff ↗
  • 2.0
    record
    2022-05-11 · diff ↗
  • R
    R 4.2.0 released · 2022-04-22
  • R
    R 4.1.0 released · 2021-05-18
  • R
    R 4.0.0 released · 2020-04-24
  • R
    R 3.6.0 released · 2019-04-26
  • 1.6.3
    record
    2018-11-17 · diff ↗
  • 1.6.2
    record
    2018-10-14 · diff ↗ ·
    added 1 export
    wTO.rep_measure
Show 12 earlier eventsHide 12 earlier events

Package metadata

First published
2017-05-29
Total releases
16 / 9 yrs
License
GPL-2 OSI
Bundled data
149 KB / 4 files
Download size
91 KB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("wTO")

The package provides a citation file that builds its entry when R runs it. Run citation() to see it.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for wTO version 2.1 [Data set]. HJJB, LLC. Data release v2026-10-20. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-20, which the citation names so these numbers can be found later. More on citing and the projects behind them.

Report a problem with this page →

Privacy choices

These apply to this browser and are stored on this device only. Nothing about your choice is sent to us.

Read the privacy policy