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valytics

Statistical Methods for Analytical Method Comparison and Validation

v0.4.1 · Feb 19, 2026 · GPL-3

Description

Provides statistical methods for analytical method comparison and validation studies. Implements Bland-Altman analysis for assessing agreement between measurement methods (Bland & Altman (1986) <doi:10.1016/S0140-6736(86)90837-8>), Passing-Bablok regression for non-parametric method comparison (Passing & Bablok (1983) <doi:10.1515/cclm.1983.21.11.709>), and Deming regression accounting for measurement error in both variables (Linnet (1993) <doi:10.1093/clinchem/39.3.424>). Also includes tools for setting quality goals based on biological variation (Fraser & Petersen (1993) <doi:10.1093/clinchem/39.7.1447>) and calculating Six Sigma metrics, precision experiments with variance component analysis, precision profiles for functional sensitivity estimation (Kroll & Emancipator (1993) <https://pubmed.ncbi.nlm.nih.gov/8448849/>). Commonly used in clinical laboratory method validation. Provides publication-ready plots and comprehensive statistical summaries.

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CRAN Check Status

13 OK
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r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK

Check History

OK 13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Jun 9, 2026
NOTE 12 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Jun 8, 2026
NOTE r-devel-linux-x86_64-debian-gcc

Rd \usage sections

Fatal error: cannot create 'R_TempDir'
The \usage entries for S3 methods should use the \method markup and not
their full name.
See chapter ‘Writing R documentation files’ in the ‘Writing R
Extensions’ manual.
WARNING 12 OK · 0 NOTE · 1 WARNING · 0 ERROR · 0 FAILURE Jun 7, 2026
WARNING r-devel-linux-x86_64-debian-gcc

Rd files

cannot open the connection
cannot open the connection
cannot open the connection
cannot open the connection
cannot open the connection
cannot open the connection
cannot open the connection
cannot open the connection
problems found in ‘deming_regression.Rd’, ‘glucose_methods.Rd’, ‘pb_regression.Rd’, ‘plot.ba_analysis.Rd’, ‘plot.deming_regression.Rd’, ‘plot.pb_regression.Rd’, ‘plot.precision_profile.Rd’, ‘plot.precision_study.Rd’
OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026

Dependency Network

Dependencies Reverse dependencies ggplot2 robslopes valytics

Version History

4 tracked
new 0.4.1 Mar 10, 2026
updated 0.4.1 ← 0.4.0 diff Feb 18, 2026
updated 0.4.0 ← 0.3.0 diff Feb 9, 2026
new 0.3.0 Jan 21, 2026