Genome-Wide DNA Methylation Sites Screening by Use of Training and Testing Samples
Overview
A screening process utilizing training and testing samples to filter out uninformative DNA methylation sites. Surrogate variables (SVs) of DNA methylation are included in the filtering process to explain unknown factor effects. This package also provides two screening functions for screening high-dimensional predictors when the events are rare. The firth method is called 'Rare-Screening' which employs a repeated random sampling with replacement and using linear modeling with Bayes adjustment. The Second method is called 'Firth-ttScreening' which uses 'ttScreening' method with additional Firth correction term in the maximum likelihood for the logistic regression model. These methods handle the high-dimensionality and low event rates.
Install
Health
- OK13 OK2026-08-04
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-06-27
- ERROR12 OK, 1 ERROR2026-06-21
- OK13 OK2026-06-09
Show 11 earlier changesHide 11 earlier changes
- ERROR12 OK, 1 ERROR2026-06-08
- WARNING12 OK, 1 WARNING2026-06-07
- OK13 OK2026-05-11
- WARNING12 OK, 1 WARNING2026-05-10
- OK13 OK2026-05-06
- ERROR12 OK, 1 ERROR2026-05-04
- OK14 OK2026-04-16
- ERROR13 OK, 1 ERROR2026-04-15
- OK14 OK2026-04-09
- ERROR13 OK, 1 ERROR2026-04-07
- OK14 OK2026-03-10
Documentation
- Help pages
- 7includes a package overview page
- Examples that run
- 0%3 never run
- Exported functions with examples
- 50%
- Documented parameters
- 100%
- Return-value docs
- 100%
- Help pages citing references
- 71%
Downloads
Dependencies
Installing ttScreening adds 11 packages (5 with compiled code, 5.3 MB of source tarballs). Heaviest: brglm2 2.3 MB, colorspace 2.0 MB, matrixStats 207 KB. 2 more not on CRAN are not measured.
Code & Tests
People & History
Previously maintained by Xin Tong (1.0).
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- 1.8Latest
- unarchivedReturned to CRAN2025-07-04
- 1.72025-07-04 · diff ↗
- archivedRemoved from CRAN2025-06-13issues were not corrected despite reminders
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- RR 4.1.0 released · 2021-05-18
- RR 4.0.0 released · 2020-04-24
- RR 3.6.0 released · 2019-04-26
- 1.62018-10-12 · diff ↗
- RR 3.5.0 released · 2018-04-23
- RR 3.4.0 released · 2017-04-21
- RR 3.3.0 released · 2016-05-03
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Package metadata
- First published
- 2013-10-05
- Total releases
- 9 / 13 yrs
- License
- Artistic-2.0 OSI
- Download size
- 14 KB
Cite
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Run in R for the authors' preferred citation:
citation("ttScreening")This package has no citation file, so citation() returns this entry built from DESCRIPTION.
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