Transcription Elongation Profiling
Overview
The general principle relies on calculating the cumulative signal of nascent RNA sequencing over the gene body of any given gene or transcription unit. 'tepr' can identify transcription attenuation sites by comparing profile to a null model which assumes uniform read density over the entirety of the transcription unit. It can also identify increased or diminished transcription attenuation by comparing two conditions. Besides rigorous statistical testing and high sensitivity, a major feature of 'tepr' is its ability to provide the elongation pattern of each individual gene, including the position of the main attenuation point when such a phenomenon occurs. Using 'tepr', users can visualize and refine genome-wide aggregated analyses of elongation patterns to robustly identify effects specific to subsets of genes. These metrics are suitable for internal comparisons (between genes in each condition) and for studying elongation of the same gene in different conditions or comparing it to a perfect theoretical uniform elongation.
- Remove Additional_repositories from DESCRIPTION.
From NEWS in the release
Install
Health
- OK13 OK2026-10-01
- ERROR12 OK, 1 ERROR2026-09-24
- OK13 OK2026-08-04
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-06-24
Show 12 earlier changesHide 12 earlier changes
- ERROR11 OK, 1 NOTE, 1 ERROR2026-06-19
- NOTE12 OK, 1 NOTE2026-06-17
- OK13 OK2026-06-14
- ERROR11 OK, 2 ERROR2026-06-07
- OK13 OK2026-06-03
- ERROR11 OK, 2 ERROR2026-05-30
- OK13 OK2026-05-10
- ERROR12 OK, 1 ERROR2026-05-03
- OK13 OK2026-05-01
- ERROR12 OK, 1 ERROR2026-04-28
- OK12 OK2026-04-25
- NOTE12 OK, 2 NOTE2026-03-10
Documentation
- Help pages
- 24
- Examples that run
- 75%18 run in a plain check · 4 only when donttest examples are enabled (R CMD check --as-cran) · 2 never run
- Exported functions with examples
- 100%
- Documented parameters
- 99%
- Return-value docs
- 100%
- Help pages citing references
- 0%
Downloads
Dependencies
Installing tepr adds 47 packages (26 with compiled code, 34 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, Rcpp 1.8 MB. 5 more not on CRAN are not measured.
Code & Tests
Datasets
People & History
Pick two releases to compare their code metrics.
- 1.1.17Latest
- RR 4.6.0 released · 2026-04-24
- 1.1.152026-03-06 · diff ↗
- 1.1.142026-01-28 · diff ↗
- 1.1.132025-12-12 · diff ↗
- 1.1.122025-11-04 · diff ↗
- 1.1.112025-10-24 · diff ↗
- 1.1.102025-09-03 · diff ↗
- unarchivedReturned to CRAN2025-08-19
- 1.1.9
- archivedRemoved from CRAN2025-08-18multiple policy violations On Internet access Repeatedly spamming personal addresses of team member in HTML
- 1.1.82025-04-22
- RR 4.5.0 released · 2025-04-11
Package metadata
- First published
- 2025-04-22
- Total releases
- 9 / 1 yrs
- License
- GPL-3 OSI
- Minimum R
- ≥ 4.4
- Download size
- 3.5 MB
Cite
Cite this package
Run in R for the authors' preferred citation:
citation("tepr")This package has no citation file, so citation() returns this entry built from DESCRIPTION.
Cite the R Observatory
For a number measured here: a download total, a coverage figure, an archival date.
From data release v2026-10-25, which the citation names so these numbers can be found later. More on citing and the projects behind them.