Single-Sample Mutation-Based Pathway Analysis
Overview
A systematic bioinformatics tool to perform single-sample mutation-based pathway analysis by integrating somatic mutation data with the Protein-Protein Interaction (PPI) network. In this method, we use local and global weighted strategies to evaluate the effects of network genes from mutations according to the network topology and then calculate the mutation-based pathway enrichment score (ssMutPES) to reflect the accumulated effect of mutations of each pathway. Subsequently, the ssMutPES profiles are used for unsupervised spectral clustering to identify cancer subtypes.
Install
Health
- OK13 OK2026-08-04
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-06-08
- ERROR12 OK, 1 ERROR2026-06-07
- OK14 OK2026-03-10
Documentation
- Help pages
- 23
- Examples that run
- 100%11 run in a plain check
- Exported functions with examples
- 92%
- Documented parameters
- 94%
- Return-value docs
- 100%
- Help pages citing references
- 0%
- ssMutPA HTML
Downloads
Dependencies
Installing ssMutPA adds 24 packages (10 with compiled code, 22 MB of source tarballs). Heaviest: ggplot2 6.0 MB, igraph 4.8 MB, ggridges 2.1 MB. 1 more not on CRAN is not measured.
Code & Tests
Datasets
People & History
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- 0.1.2Latest
- 0.1.12024-10-10 · diff ↗
- RR 4.4.0 released · 2024-04-24
- 0.1.02024-04-16
- RR 4.3.0 released · 2023-04-21
Package metadata
- First published
- 2024-04-16
- Total releases
- 3 / 2 yrs
- License
- GPL (>= 2) OSI
- Minimum R
- ≥ 4.0.0
- Bundled data
- 673 KB / 11 files
- Download size
- 2.0 MB
Cite
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