simtte
1.0.2Simulate Bespoke Time-to-Event Models Using ODEs
Overview
Simulates time-to-event (survival) datasets for clinical trial design and analysis using ordinary differential equation (ODE) models solved via the 'mrgsolve' backend. Built-in Weibull and flexible M-spline baseline hazard models are provided out of the box, and fully bespoke hazard models can be implemented as custom 'mrgsolve' ODE systems. Event times are generated by inverse transform sampling from the resulting cumulative hazard functions. See Bender et al. (2005) doi:10.1002/sim.2059 for the inverse transform sampling methodology and Royston and Parmar (2002) doi:10.1002/sim.1203 for flexible parametric survival models.
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- OK2026-08-0413 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
- NOTE2026-08-0112 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
- OK2026-07-128 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
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Checks run against github.com/csetraynor/simtte on 2026-08-16.
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2 releases. R releases are shown for context.
- 1.0.2Latest
- 1.0.12026-07-11
- RR 4.6.0 released · 2026-04-24
Package metadata
- First published
- 2026-07-11
- Total releases
- 2 / 1 yrs
- License
- GPL (>= 2) OSI
- Download size
- 32 KB
- Installed size
- not tracked yet
- With dependencies
- not tracked yet
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