scModels
1.0.5Fitting Discrete Distribution Models to Count Data
Overview
Provides functions for fitting discrete distribution models to count data. Included are the Poisson, the negative binomial, the Poisson-inverse gaussian and, most importantly, a new implementation of the Poisson-beta distribution (density, distribution and quantile functions, and random number generator) together with a needed new implementation of Kummer's function (also: confluent hypergeometric function of the first kind). Three different implementations of the Gillespie algorithm allow data simulation based on the basic, switching or bursting mRNA generating processes. Moreover, likelihood functions for four variants of each of the three aforementioned distributions are also available. The variants include one population and two population mixtures, both with and without zero-inflation. The package depends on the 'MPFR' libraries (https://www.mpfr.org/) which need to be installed separately (see description at https://github.com/fuchslab/scModels). This package is supplement to the paper "A mechanistic model for the negative binomial distribution of single-cell mRNA counts" by Lisa Amrhein, Kumar Harsha and Christiane Fuchs (2019) doi:10.1101/657619 available on bioRxiv.
Install
Health
- OK2026-08-0413 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
- NOTE2026-08-0112 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
- OK2026-06-067 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
Documentation
- Examples that run
- 100%
- Documented parameters
- 52%
- Return-value docs
- 0%
- References docs
- 0%
Downloads
Dependencies
Nothing depends on this yet.
Code & Tests
People & History
6 releases. Pick two to compare their code metrics. R releases are shown for context.
- 1.0.5Latest
- unarchivedReturned to CRAN2026-06-05
- RR 4.6.0 released · 2026-04-24
- archivedRemoved from CRAN2026-03-09issues were not corrected despite reminders
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- 1.0.42023-01-24 · diff ↗
- RR 4.2.0 released · 2022-04-22
- 1.0.32022-03-29 · diff ↗
- unarchivedReturned to CRAN2022-03-29
- archivedRemoved from CRAN2022-03-17check problems were not corrected in time Does not install with current (trunk) mpfr headers
- RR 4.1.0 released · 2021-05-18
- 1.0.22021-02-26 · diff ↗
- RR 4.0.0 released · 2020-04-24
- unarchivedReturned to CRAN2019-09-03
Show 4 earlier events
- 1.0.12019-09-02 · diff ↗
- archivedRemoved from CRAN2019-09-01installation warnings were not corrected Warnings with mpfr 4.x, which is an undeclared and untested 'SystemRequirements'
- 1.0.02019-06-13
- RR 3.6.0 released · 2019-04-26
Package metadata
- First published
- 2026-06-05
- Total releases
- 6 / 1 yrs
- License
- GPL-3 OSI
- Minimum R
- ≥ 3.1.0
- Download size
- 40 KB
- Installed size
- not tracked yet
- With dependencies
- not tracked yet
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