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scMappR

1.0.12Package record

Single Cell Mapper

0packages depend
3.9Kdownloads / year
–test coverage
12/13flavors OK

Overview

About

The single cell mapper (scMappR) R package contains a suite of bioinformatic tools that provide experimentally relevant cell-type specific information to a list of differentially expressed genes (DEG). The function "scMappR_and_pathway_analysis" reranks DEGs to generate cell-type specificity scores called cell-weighted fold-changes. Users input a list of DEGs, normalized counts, and a signature matrix into this function. scMappR then re-weights bulk DEGs by cell-type specific expression from the signature matrix, cell-type proportions from RNA-seq deconvolution and the ratio of cell-type proportions between the two conditions to account for changes in cell-type proportion. With cwFold-changes calculated, scMappR uses two approaches to utilize cwFold-changes to complete cell-type specific pathway analysis. The "process_dgTMatrix_lists" function in the scMappR package contains an automated scRNA-seq processing pipeline where users input scRNA-seq count data, which is made compatible for scMappR and other R packages that analyze scRNA-seq data. We further used this to store hundreds up regularly updating signature matrices. The functions "tissue_by_celltype_enrichment", "tissue_scMappR_internal", and "tissue_scMappR_custom" combine these consistently processed scRNAseq count data with gene-set enrichment tools to allow for cell-type marker enrichment of a generic gene list (e.g. GWAS hits). Reference: Sokolowski,D.J., Faykoo-Martinez,M., Erdman,L., Hou,H., Chan,C., Zhu,H., Holmes,M.M., Goldenberg,A. and Wilson,M.D. (2021) Single-cell mapper (scMappR): using scRNA-seq to infer cell-type specificities of differentially expressed genes. NAR Genomics and Bioinformatics. 3(1). Iqab011. doi:10.1093/nargab/lqab011.

Install

Health

CRAN checks
1ERROR12OK
Check messages
ERRORpackage dependenciesr-patched-linux-x86_64
Package required but not available: ‘GSVA’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
Additional issues

CRAN check page ↗

Slowest check: 13.8 min · r-oldrel-windows-x86_64
Status changes
  • ERROR12 OK, 1 ERROR2026-10-15
  • WARNING12 OK, 1 WARNING2026-09-25
  • OK13 OK2026-09-24
  • ERROR12 OK, 1 ERROR2026-09-17
  • OK13 OK2026-08-04
Show 14 earlier changesHide 14 earlier changes
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK13 OK2026-07-26
  • ERROR12 OK, 1 ERROR2026-07-19
  • OK13 OK2026-06-27
  • ERROR12 OK, 1 ERROR2026-06-21
  • OK13 OK2026-06-09
  • ERROR12 OK, 1 ERROR2026-06-08
  • OK13 OK2026-05-10
  • ERROR12 OK, 1 ERROR2026-05-03
  • OK13 OK2026-04-30
  • ERROR12 OK, 2 ERROR2026-04-09
  • OK14 OK2026-03-16
  • ERROR13 OK, 1 ERROR2026-03-13
  • OK14 OK2026-03-10
Advisories

none known

Documentation

In release 1.0.12
READMEYes · 1,381 wordsVignettesYes · 1 · dynamicNEWSNoCitation fileNoWebsitenot declared in DESCRIPTION
Help pages
34
Examples that run
38%13 run in a plain check · 21 only when donttest examples are enabled (R CMD check --as-cran)
Exported functions with examples
100%
Documented parameters
100%
Return-value docs
100%
Help pages citing references
0%

Downloads

3.9K
CRAN downloads in the past year
Rank #8,965 · ~11/day · ~324/mo
Daily download trend is not available in this view yet.
38630 days
1.1K90 days
3.9K1 year
Compare downloads with other packages →
Also on80 r2u

Dependencies

Declared dependencies
15 external dependencies (excludes base and recommended)

Installing scMappR adds 165 packages (94 with compiled code, 143 MB of source tarballs). Heaviest: BH 14 MB, stringi 11 MB, ggplot2 6.0 MB. 3 more not on CRAN are not measured.

Depends (1)
R >= 4.0.0
LinkingTo (0)
none
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Datasets

People & History

People (9)
Author, Maintainer since 0.1 (2020)
Author · added in 0.1.4
Author · added in 0.1.4
Author · added in 0.1.4
Author · added in 0.1.4
Author · added in 0.1.4
Releases (13)

Pick two releases to compare their code metrics.

  • R
    R 4.6.0 released · 2026-04-24
  • unarchivedReturned to CRAN
    2025-06-25
  • 1.0.12Latest
    record
    2025-06-25 · current release · diff ↗
  • archivedRemoved from CRAN
    2025-06-02
    requires archived package 'limSolve'
  • R
    R 4.5.0 released · 2025-04-11
  • R
    R 4.4.0 released · 2024-04-24
  • 1.0.11
    record
    2023-06-30 · diff ↗
  • R
    R 4.3.0 released · 2023-04-21
  • unarchivedReturned to CRAN
    2023-02-18
  • 1.0.10
    record
    2023-02-18 · diff ↗
  • archivedRemoved from CRAN
    2022-12-21
    email to the maintainer was undeliverable
  • R
    R 4.2.0 released · 2022-04-22
  • 1.0.9
    record
    2022-03-07 · diff ↗
  • 1.0.7
    record
    2021-10-16 · diff ↗
  • R
    R 4.1.0 released · 2021-05-18
  • 1.0.2
    record
    2021-05-15 · diff ↗
Show 9 earlier eventsHide 9 earlier events
  • 1.0.1
    record
    2021-03-30 · diff ↗
  • 1.0.0
    record
    2021-03-22 · diff ↗
  • 0.1.5
    record
    2020-11-30 · diff ↗ ·
    added 2 exports
    compare_deconvolution_methods, cwFoldChange_evaluate
  • 0.1.4
    record
    2020-09-02 · diff ↗ ·
    added 1 export
    get_signature_matrices
  • 0.1.3
    record
    2020-07-21 · diff ↗ ·
    added 1 export
    two_method_pathway_enrichment
  • R
    R 4.0.0 released · 2020-04-24
  • 0.1.1
    record
    2020-03-06 · diff ↗
  • 0.1
    record
    2020-03-04
  • R
    R 3.6.0 released · 2019-04-26

Package metadata

First published
2020-03-04
Total releases
13 / 6 yrs
License
GPL-3 OSI
Minimum R
≥ 4.0.0
Bundled data
529 KB / 5 files
Download size
651 KB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("scMappR")
Sokolowski, D., Chan, C., Erdman, L., Faykoo-Martinez, M., Goldenberg, A., Holmes, M., Hou, H., Wilson, M., & Zhu, H. (2025). scMappR: Single Cell Mapper (Version 1.0.12) [Computer software]. https://doi.org/10.32614/CRAN.package.scMappR

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for scMappR version 1.0.12 [Data set]. HJJB, LLC. Data release v2026-10-23. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-23, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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