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rplec

0.1.3

Placental Epigenetic Clock to Estimate Aging by DNA Methylation

0packages depend
1.9Kdownloads / year
92.5%test coverage
13/13checks pass

Overview

About
Maintained by Herdiantri SufriyanaFirst published 2025-01-271 releasesCRAN page ↗

Placental epigenetic clock to estimate aging based on gestational age using DNA methylation levels, so called placental epigenetic clock (PlEC). We developed a PlEC for the 2024 Placental Clock DREAM Challenge (https://www.synapse.org/Synapse:syn59520082/wiki/628063). Our PlEC achieved the top performance based on an independent test set. PlEC can be used to identify accelerated/decelerated aging of placenta for understanding placental dysfunction-related conditions, e.g., great obstetrical syndromes including preeclampsia, fetal growth restriction, preterm labor, preterm premature rupture of the membranes, late spontaneous abortion, and placental abruption. Detailed methodologies and examples are documented in our vignette, available at https://herdiantrisufriyana.github.io/rplec/doc/placental_aging_analysis.html.

Install

Health

CRAN checks
13OK
Slowest check: 8.0 min · r-devel-windows-x86_64
Code health
Yes
Tests · ratio 0.20
92.5%
Coverage · measured lines
100%
Documentation · exports
13
Dependencies · direct
Check history
  • OK2026-08-04
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • NOTE2026-08-01
    12 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • OK2026-07-15
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-07-10
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • OK2026-07-03
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
Show 6 earlier snapshots
  • ERROR2026-07-01
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • OK2026-06-27
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-06-20
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • OK2026-04-16
    14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-04-09
    12 OK · 0 NOTE · 0 WARNING · 2 ERROR · 0 FAILURE
  • OK2026-03-10
    14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

Documentation
READMEYes · 479 wordsVignettesYes · dynamicpkgdown siteNoNEWSNoCode of conductNoContributing guideNo
Examples that run
50%
Documented parameters
100%
Return-value docs
100%
References docs
0%

Downloads

1.9K
CRAN downloads in the past year
Rank #20,696 · ~5/day · ~157/mo
Daily download trend is not available in this view yet.
16330 days
53290 days
1.9K1 year
Compare downloads with other packages →
Also on169 r2u

Dependencies

Declared dependencies
13 external dependencies (excludes base and recommended)
Depends (1)
R >= 4.4
LinkingTo (0)
none
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Code & Tests

Datasets

People & History

People (2)
Maintainer (1)
Author, Maintainer
Authors (2)
Author, Maintainer
Package Timeline

1 release. R releases are shown for context.

  • R
    R 4.6.0 released · 2026-04-24
  • 0.1.3Latest
    2026-03-10 · current release
  • R
    R 4.5.0 released · 2025-04-11

Package metadata

First published
2025-01-27
Total releases
1 / 1 yrs
License
MIT + file LICENSE OSI
Minimum R
≥ 4.4
Bundled data
2.8 MB / 8 files
Download size
3.3 MB
Installed size
not tracked yet
With dependencies
not tracked yet

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("rplec")
Sufriyana, H., & Su, E. C. (2025). rplec: Placental Epigenetic Clock to Estimate Aging by DNA Methylation (Version 0.1.3) [Computer software]. https://doi.org/10.32614/CRAN.package.rplec

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for rplec version 0.1.3 [Data set]. HJJB, LLC. Data release v2026-08-18. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-18, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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