Skip to content

rChEA3

R Client for the 'ChEA3' Transcription Factor Enrichment API

v0.2.0 · Oct 15, 2025 · MIT + file LICENSE
CRAN GitHub Mirror

Description

Interface to the 'ChEA3' transcription factor enrichment API. 'ChEA3' integrates evidence from ChIP-seq, co-expression, and literature resources to prioritize transcription factors regulating a given set of genes. This package provides convenient R functions to query the API, retrieve ranked results across collections (including integrated scores), and standardize output for downstream analysis in R/Bioconductor workflows. See <https://maayanlab.cloud/chea3/> or Keenan (2019) <doi:10.1093/nar/gkz446> for further details.

Downloads

243

Last 30 days

18452nd

575

Last 90 days

1.1K

Last year

Trend: +35.8% (30d vs prior 30d)

CRAN Check Status

14 OK
Show all 14 flavors
Flavor Status
r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK

Check History

OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 31, 2026
ERROR 13 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Mar 27, 2026
ERROR r-devel-windows-x86_64

re-building of vignette outputs

Error(s) in re-building vignettes:
--- re-building 'rChEA3.Rmd' using rmarkdown

Quitting from rChEA3.Rmd:56-59 [submit]
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
<error/rlang_error>
Error:
! ChEA3 API request f
...[truncated]...
with status 503. Please try again later or check the API status at https://maayanlab.cloud/chea3/
--- failed re-building 'rChEA3.Rmd'

SUMMARY: processing the following file failed:
  'rChEA3.Rmd'

Error: Vignette re-building failed.
Execution halted
OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026

Dependency Network

Dependencies Reverse dependencies cli crayon dplyr ggplot2 httr jsonlite lubridate rlang tidyselect writexl rChEA3

Version History

new 0.2.0 Mar 10, 2026