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phase1PRMD

1.0.2Package record

Personalized Repeated Measurement Design for Phase I Clinical Trials

0packages depend
2.7Kdownloads / year
–test coverage
11/13flavors OK

Overview

About
Maintained by Lu ZhangCRAN page ↗

Implements Bayesian phase I repeated measurement design that accounts for multidimensional toxicity endpoints and longitudinal efficacy measure from multiple treatment cycles. The package provides flags to fit a variety of model-based phase I design, including 1 stage models with or without individualized dose modification, 3-stage models with or without individualized dose modification, etc. Functions are provided to recommend dosage selection based on the data collected in the available patient cohorts and to simulate trial characteristics given design parameters. Yin, Jun, et al. (2017) doi:10.1002/sim.7134.

Changes in 1.0.2

Major changes

Remove the dependence on package phase1RMD

From NEWS.md in the release

Install

Health

CRAN checks
2NOTE11OK
Check messages
NOTECRAN incoming feasibilityr-devel-linux-x86_64-debian-clang, r-devel-linux-x86_64-debian-gcc
Maintainer: ‘Lu Zhang <luzhangstat@gmail.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Lu",
                      family = "Zhang",
                      role = c("aut", "cre"),
                      email = "luzhangstat@gmail.com"),
               person(given = "Jun",
                      family = "Yin",
                      role = "aut"))
as necessary.

CRAN check page ↗

Slowest check: 2.1 min · r-oldrel-windows-x86_64
Status changes
  • NOTE11 OK, 2 NOTENow
  • NOTE12 OK, 2 NOTE2026-03-10
Advisories

none known

Documentation

In release 1.0.2
READMEYes · 107 wordsVignettesNoNEWSYes · 33% structured · mentions 1.0.2Citation fileNoWebsitenot declared in DESCRIPTION
Help pages
16
Examples that run
60%6 run in a plain check · 4 hold no code
Exported functions with examples
86%
Documented parameters
98%
Return-value docs
86%
Help pages citing references
0%

Downloads

2.7K
CRAN downloads in the past year
Rank #18,688 · ~7/day · ~225/mo
Daily download trend is not available in this view yet.
23630 days
70790 days
2.7K1 year
Compare downloads with other packages →
Also on68 r2u1 autocran

Dependencies

Declared dependencies
11 external dependencies (excludes base and recommended)

Installing phase1PRMD adds 62 packages (33 with compiled code, 50 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, bslib 5.6 MB.

Depends (4)
R >= 3.0.0codaggplot2stats
LinkingTo (0)
none
Suggests (0)
none
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Datasets

People & History

People (from the free-text Author field) (2)

Maintainer since 1.0.1 (2019)

Releases (2)

Pick two releases to compare their code metrics.

  • R
    R 4.6.0 released · 2026-04-24
  • R
    R 4.5.0 released · 2025-04-11
  • R
    R 4.4.0 released · 2024-04-24
  • R
    R 4.3.0 released · 2023-04-21
  • R
    R 4.2.0 released · 2022-04-22
  • R
    R 4.1.0 released · 2021-05-18
  • R
    R 4.0.0 released · 2020-04-24
  • 1.0.2Latest
    record
    2020-03-09 · current release · diff ↗
  • R
    R 3.6.0 released · 2019-04-26
  • 1.0.1
    record
    2019-02-03
  • R
    R 3.5.0 released · 2018-04-23

Package metadata

First published
2019-02-03
Total releases
2 / 7 yrs
License
GPL (>= 2) OSI
Minimum R
≥ 3.0.0
Bundled data
22 KB / 3 files
Download size
65 KB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("phase1PRMD")

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for phase1PRMD version 1.0.2 [Data set]. HJJB, LLC. Data release v2026-10-26. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-26, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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