nonmem2rx
Converts 'NONMEM' Models to 'rxode2'
Description
'NONMEM' has been a tool for running nonlinear mixed effects models since the 80s and is still used today (Bauer 2019 <doi:10.1002/psp4.12404>). This tool allows you to convert 'NONMEM' models to 'rxode2' (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>) and with simple models 'nlmixr2' syntax (Fidler et al (2019) <doi:10.1002/psp4.12445>). The 'nlmixr2' syntax requires the residual specification to be included and it is not always translated. If available, the 'rxode2' model will read in the 'NONMEM' data and compare the simulation for the population model ('PRED') individual model ('IPRED') and residual model ('IWRES') to immediately show how well the translation is performing. This saves the model development time for people who are creating an 'rxode2' model manually. Additionally, this package reads in all the information to allow simulation with uncertainty (that is the number of observations, the number of subjects, and the covariance matrix) with a 'rxode2' model. This is complementary to the 'babelmixr2' package that translates 'nlmixr2' models to 'NONMEM' and can convert the objects converted from 'nonmem2rx' to a full 'nlmixr2' fit.
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CRAN Check Status
Show all 13 flavors
| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | OK |
| r-devel-linux-x86_64-debian-gcc | OK |
| r-devel-linux-x86_64-fedora-clang | OK |
| r-devel-linux-x86_64-fedora-gcc | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | OK |
| r-oldrel-macos-x86_64 | OK |
| r-oldrel-windows-x86_64 | OK |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
| r-release-macos-x86_64 | OK |
| r-release-windows-x86_64 | OK |
Check History
OK 13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Jun 9, 2026
ERROR 12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Jun 8, 2026
whether package can be installed
install log ‘’ does not exist
OK 12 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Apr 25, 2026
NOTE 11 OK · 3 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Apr 22, 2026
installed package size
installed size is 9.2Mb
sub-directories of 1Mb or more:
libs 5.2Mb
mods 3.3Mb
installed package size
installed size is 9.6Mb
sub-directories of 1Mb or more:
libs 5.5Mb
mods 3.4Mb
installed package size
installed size is 6.6Mb
sub-directories of 1Mb or more:
libs 2.6Mb
mods 3.3Mb
ERROR 10 OK · 3 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Apr 18, 2026
whether package can be installed
Installation failed. See 'd:/Rcompile/CRANpkg/local/4.6/nonmem2rx.Rcheck/00install.out' for details.
installed package size
installed size is 9.2Mb
sub-directories of 1Mb or more:
libs 5.2Mb
mods 3.3Mb
installed package size
installed size is 9.6Mb
sub-directories of 1Mb or more:
libs 5.5Mb
mods 3.4Mb
installed package size
installed size is 6.6Mb
sub-directories of 1Mb or more:
libs 2.6Mb
mods 3.3Mb
NOTE 11 OK · 3 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
installed package size
installed size is 9.2Mb
sub-directories of 1Mb or more:
libs 5.2Mb
mods 3.3Mb
installed package size
installed size is 9.6Mb
sub-directories of 1Mb or more:
libs 5.5Mb
mods 3.4Mb
installed package size
installed size is 6.6Mb
sub-directories of 1Mb or more:
libs 2.6Mb
mods 3.3Mb