Joint Sparse Regression & Network Learning with Missing Data
Overview
Simultaneously estimates sparse regression coefficients and response network structure in multivariate models with missing data. Unlike traditional approaches requiring imputation, handles missingness natively through unbiased estimating equations (MCAR/MAR compatible). Employs dual L1 regularization with automated selection via cross-validation or information criteria. Includes parallel computation, warm starts, adaptive grids, publication-ready visualizations, and prediction methods. Ideal for genomics, neuroimaging, and multi-trait studies with incomplete high-dimensional outcomes. See Zeng et al. (2025) doi:10.48550/arXiv.2507.05990.
> **Major release.** Architecture rebuilt for speed, stability, and cleaner workflows. **Recommend all users upgrade.**
Highlights
- **3–5× faster** on typical problems via rewriting core kernels in **RcppArmadillo**.
- **Adaptive grid and lambda search** that scales to large problems with fewer evaluations.
- **Element-wise precise penalty control** for both coefficients and network edges.
Algorithm & Features
- Consistent search strategy in
missoNet()andcv.missoNet(). - **penalty customization** through
beta.pen.factorandtheta.pen.factor, enabling exclusion of predictors or structured sparsity patterns. relax.netoption for **de-biased network estimation**: refits the active edge set without L1 penalties to reduce bias in the precision matrix.- Support multiple graphical lasso backends (e.g., glassoFast (default) / glasso) with automatic selection and fallbacks.
- Smarter defaults and **data-aware initialization** tuned to dimensionality, missingness, and conditioning.
- **Full parallelization** for cross-validation and grid evaluation.
Show all changes in 1.5.1Hide the rest of the changes in 1.5.1
Performance & Robustness
- Vectorized algebra and memory reuse; internal benchmarks show **3–5× speedups**
- The **warm-start** strategy has been rewritten to enhance stability.
- Tighter line search and stopping in FISTA; **fewer oscillations**.
- Epsilon‑safe numerics; strict finite‑value checks.
Visualization & UX
- **Upgraded** S3
plot()for publication-quality output. - Clearer progress and diagnostics (stages, backend, convergence).
Documentation
- **New vignettes: introduction, advanced features, case studies**.
- Cross-references and examples aligned across
missoNet()andcv.missoNet(); arguments and return values documented consistently.
Bug Fixes
- Fixed
Infpropagation in preprocessing. - Fixed cross-package reference linking.
- Removed unused external data to reduce package size.
- Miscellaneous bugs.
> **Compatibility:** Minor API changes; refined defaults. See ?missoNet, ?cv.missoNet.
From NEWS.md in the release
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-06-08
- WARNING12 OK, 1 WARNING2026-06-07
- OK12 OK2026-04-25
Show 3 earlier changesHide 3 earlier changes
- NOTE12 OK, 2 NOTE2026-04-22
- ERROR11 OK, 2 NOTE, 1 ERROR2026-04-18
- NOTE12 OK, 2 NOTE2026-03-10
Documentation
- Help pages
- 6includes a package overview page
- Examples that run
- 100%6 run in a plain check
- Exported functions with examples
- 100%
- Documented parameters
- 76%
- Return-value docs
- 100%
- Help pages citing references
- 33%
Downloads
Repository
Stars over time
Releases over time
5 development-tooling and community-health practices detected across 3 families in the upstream repository
Checks run against github.com/yixiao-zeng/missonet on 2026-10-21.
The R CMD check workflow runs on Linux
Dependencies
Installing missoNet adds 10 packages (5 with compiled code, 9.7 MB of source tarballs). Heaviest: circlize 2.4 MB, colorspace 2.0 MB, Rcpp 1.8 MB. 1 more not on CRAN is not measured.
Code & Tests
People & History
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- RR 4.6.0 released · 2026-04-24
- 1.5.1Latest
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- unarchivedReturned to CRAN2023-07-19
- archivedRemoved from CRAN2023-07-19issues were not corrected in time
- 1.2.02023-07-19 · diff ↗
- 1.1.02023-05-11 · diff ↗
- RR 4.3.0 released · 2023-04-21
- 1.0.02022-10-10
- RR 4.2.0 released · 2022-04-22
Package metadata
- First published
- 2022-10-10
- Total releases
- 4 / 4 yrs
- License
- GPL-2 OSI
- Minimum R
- ≥ 3.6.0
- Download size
- 811 KB
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