Lightweight Iterative Geneset Enrichment
Overview
Gene Set Enrichment Analysis (GSEA) is a computational method that determines whether an a priori defined set of genes shows statistically significant, concordant differences between two biological states. The original algorithm is detailed in Subramanian et al. with 'Java' implementations available through the Broad Institute (Subramanian et al. 2005 doi:10.1073/pnas.0506580102). The 'liger' package provides a lightweight R implementation of this enrichment test on a list of values (Fan et al., 2017 doi:10.5281/zenodo.887386). Given a list of values, such as p-values or log-fold changes derived from differential expression analysis or other analyses comparing biological states, this package enables you to test a priori defined set of genes for enrichment to enable interpretability of highly significant or high fold-change genes.
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Pick two releases to compare their code metrics.
- RR 4.5.0 released · 2025-04-11
- archivedRemoved from CRAN2024-06-14issues were not corrected in time
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- RR 4.1.0 released · 2021-05-18
- 2.0.12021-01-25 · diff ↗
- 1.1.22020-07-16 · diff ↗
- RR 4.0.0 released · 2020-04-24
- RR 3.6.0 released · 2019-04-26
- 1.02019-01-03 · diff ↗
- 0.12018-06-14
- RR 3.5.0 released · 2018-04-23
Package metadata
- First published
- 2018-06-14
- Total releases
- 4 / 8 yrs
- License
- GPL-3 | file LICENSE OSI
- Minimum R
- ≥ 2.10
- Bundled data
- 1.8 MB / 2 files
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