Intelligent Predicting Response to Cancer Immunotherapy Through Systematic Modeling
Overview
Immunotherapy has revolutionized cancer treatment, but predicting patient response remains challenging. Here, we presented Intelligent Predicting Response to cancer Immunotherapy through Systematic Modeling (iPRISM), a novel network-based model that integrates multiple data types to predict immunotherapy outcomes. It incorporates gene expression, biological functional network, tumor microenvironment characteristics, immune-related pathways, and clinical data to provide a comprehensive view of factors influencing immunotherapy efficacy. By identifying key genetic and immunological factors, it provides an insight for more personalized treatment strategies and combination therapies to overcome resistance mechanisms.
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-06-09
- ERROR12 OK, 1 ERROR2026-06-08
- OK14 OK2026-03-10
Documentation
- Help pages
- 17includes a package overview page
- Examples that run
- 93%14 run in a plain check · 1 hold no code
- Exported functions with examples
- 100%
- Documented parameters
- 100%
- Return-value docs
- 100%
- Help pages citing references
- 0%
Downloads
Dependencies
Installing iPRISM adds 62 packages (33 with compiled code, 60 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, data.table 5.7 MB.
Code & Tests
Datasets
People & History
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- 0.1.1Latest2024-07-14 · current release
- RR 4.4.0 released · 2024-04-24
Package metadata
- First published
- 2024-07-14
- Total releases
- 1 / 2 yrs
- License
- GPL (>= 2) OSI
- Minimum R
- ≥ 4.1.0
- Bundled data
- 1.2 MB / 10 files
- Download size
- 1.7 MB
Cite
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