Estimation of Recombination Rate and Maternal LD in Half-Sibs
Overview
Paternal recombination rate and maternal linkage disequilibrium (LD) are estimated for pairs of biallelic markers such as single nucleotide polymorphisms (SNPs) from progeny genotypes and sire haplotypes. The implementation relies on paternal half-sib families. If maternal half-sib families are used, the roles of sire/dam are swapped. Multiple families can be considered. For parameter estimation, at least one sire has to be double heterozygous at the investigated pairs of SNPs. Based on recombination rates, genetic distances between markers can be estimated. Markers with unusually large recombination rate to markers in close proximity (i.e. putatively misplaced markers) shall be discarded in this derivation. *A pipeline is available at GitHub* https://github.com/wittenburg/hsrecombi Hampel, Teuscher, Gomez-Raya, Doschoris, Wittenburg (2018) "Estimation of recombination rate and maternal linkage disequilibrium in half-sibs" doi:10.3389/fgene.2018.00186. Gomez-Raya (2012) "Maximum likelihood estimation of linkage disequilibrium in half-sib families" doi:10.1534/genetics.111.137521.
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Documentation
- Help pages
- 23
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- Exported functions with examples
- 94%
- Documented parameters
- 100%
- Return-value docs
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- Help pages citing references
- 52%
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Installing hsrecombi adds 29 packages (19 with compiled code, 18 MB of source tarballs). Heaviest: data.table 5.7 MB, Rcpp 1.8 MB, RcppArmadillo 1.0 MB.
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- RR 4.6.0 released · 2026-04-24
- unarchivedReturned to CRAN2026-04-12
- archivedRemoved from CRAN2026-04-12issues were not corrected in time
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- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
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- RR 4.3.0 released · 2023-04-21
- 0.5.1
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- RR 4.2.0 released · 2022-04-22
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- RR 4.1.0 released · 2021-05-18
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Package metadata
- First published
- 2020-03-04
- Total releases
- 12 / 6 yrs
- License
- GPL (>= 2) OSI
- Minimum R
- ≥ 3.5.0
- Bundled data
- 12 KB / 1 file
- Download size
- 38 KB
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