Genetic-Relationship-Matrix Structural Equation Modelling (GRMSEM)
Overview
Quantitative genetics tool supporting the modelling of multivariate genetic variance structures in quantitative data. It allows fitting different models through multivariate genetic-relationship-matrix (GRM) structural equation modelling (SEM) in unrelated individuals, using a maximum likelihood approach. Specifically, it combines genome-wide genotyping information, as captured by GRMs, with twin-research-based SEM techniques, St Pourcain et al. (2017) doi:10.1016/j.biopsych.2017.09.020, Shapland et al. (2020) doi:10.1101/2020.08.14.251199.
Install
Health
NOTEdependencies in R coder-devel-linux-x86_64-fedora-clang, r-devel-linux-x86_64-fedora-gcc
Namespace in Imports field not imported from: ‘msm’ All declared Imports should be used.
- NOTE11 OK, 2 NOTENow
- NOTE12 OK, 2 NOTE2026-03-10
Documentation
- Help pages
- 11
- Examples that run
- 0%5 only when donttest examples are enabled (R CMD check --as-cran)
- Exported functions with examples
- 71%
- Documented parameters
- 100%
- Return-value docs
- 100%
- Help pages citing references
- 0%
Downloads
Repository
2 development-tooling and community-health practices detected across 2 families in the upstream repository
Checks run against gitlab.gwdg.de/beate.stpourcain/grmsem on 2026-10-21.
GitHub Pages site
Dependencies
Installing grmsem adds 16 packages (10 with compiled code, 6.4 MB of source tarballs). Heaviest: mvtnorm 1.0 MB, vctrs 1.0 MB, msm 972 KB.
Code & Tests
Datasets
People & History
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- RR 4.1.0 released · 2021-05-18
- 1.1.0Latest2021-01-29 · current release
- RR 4.0.0 released · 2020-04-24
Package metadata
- First published
- 2021-01-29
- Total releases
- 1 / 5 yrs
- License
- GPL-3 OSI
- Minimum R
- ≥ 3.5
- Bundled data
- 217 KB / 4 files
- Download size
- 919 KB
Cite
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Run in R for the authors' preferred citation:
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