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grandR

0.2.7Package record

Comprehensive Analysis of Nucleotide Conversion Sequencing Data

1packages depend
3.8Kdownloads / year
–test coverage
13/13flavors OK

Overview

About

Nucleotide conversion sequencing experiments have been developed to add a temporal dimension to RNA-seq and single-cell RNA-seq. Such experiments require specialized tools for primary processing such as GRAND-SLAM, (see 'Jürges et al' doi:10.1093/bioinformatics/bty256) and specialized tools for downstream analyses. 'grandR' provides a comprehensive toolbox for quality control, kinetic modeling, differential gene expression analysis and visualization of such data. Fast Wilcoxon tests are supported via the 'presto' package (available at https://github.com/immunogenomics/presto).

Changes in 0.2.7

Major updates

  • Removed dependency to monocle (which caused problems on the newest cran build)
  • Added wilcoxon test (optionally via presto) for differential gene expression

Smaller updates

  • More useful parameter name count.as.integer for GetTable, GetMatrix and GetData
  • Expanded code for estimation in the mixture model
  • Removed the ComputeAbsolute function
  • Reading llr and shape matrices of Grand3 output

From NEWS.md in the release

Install

Health

CRAN checks
13OK
Slowest check: 4.7 min · r-oldrel-windows-x86_64
Status changes
  • OK13 OK2026-08-05
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK13 OK2026-06-09
  • ERROR12 OK, 1 ERROR2026-06-08
  • OK12 OK2026-04-25
Show 1 earlier changeHide 1 earlier change
  • NOTE11 OK, 3 NOTE2026-03-10
Advisories

none known

Documentation

In release 0.2.7
READMEYes · 323 wordsVignettesYes · 1 · dynamicNEWSYes · 100% structured · mentions 0.2.7Citation fileYes · cites a publicationWebsitenot declared in DESCRIPTION
Help pages
126
Examples that run
90%36 run in a plain check · 2 only when donttest examples are enabled (R CMD check --as-cran) · 1 never run · 1 hold no code
Exported functions with examples
33%
Documented parameters
97%
Return-value docs
98%
Help pages citing references
0%

Downloads

3.8K
CRAN downloads in the past year
Rank #10,928 · ~10/day · ~317/mo
Daily download trend is not available in this view yet.
36530 days
95290 days
3.8K1 year
Compare downloads with other packages →
Also on388 r2u8 autocran

Repository

17Stars
4Forks
7Open issues
0Open PRs
6Releases
324Commits
21Commit identities
324 commits · Last activity 2026-01-13 · 0% stars, 30d · Discussions: 9 posts
Responsiveness
How these are sampled
PRs merged (all time)
not measured
Median days to close, 50 most recently updated closed issues
14
Median days to close, 50 most recently updated closed PRs
not measured

Stars over time

2025-08-14 · 152026-07-07 · 17
PracticesBeta

4 development-tooling and community-health practices detected across 4 families in the upstream repository

Checks run against github.com/erhard-lab/grandr on 2026-10-11.

Governance and community (1)
Issue templates
Docs source (1)
pkgdown
CRAN release process (1)
cran-comments.md
Lint, format, editor (1)
RStudio project
How this is detected·Detection ruleset v3 (2026-09-26)

Dependencies

Declared dependencies
41 external dependencies (excludes base and recommended)

Installing grandR adds 30 packages (15 with compiled code, 33 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, patchwork 3.2 MB.

Depends (1)
R >= 3.5.0
Imports (19)
LinkingTo (0)
none
Enhances (0)
none
Reverse dependencies
1direct
0indirect
Imports 1
Depends, Imports or LinkingTo, most downloaded first

Datasets

People & History

People (3)
Author, Maintainer since 0.2.0 (2022)
Contributor
Contributor · added in 0.2.7
Listed in earlier versions (2)
no longer listed · 0.2.0 to 0.2.6
no longer listed · 0.2.5 to 0.2.6
Releases (6)

Pick two releases to compare their code metrics.

  • R
    R 4.6.0 released · 2026-04-24
  • 0.2.7Latest
    record
    2026-01-14 · current release · diff ↗ ·
    removed 1 export
    ComputeAbsolute
    added 2 exports
    Renamer, Wilcoxon
  • R
    R 4.5.0 released · 2025-04-11
  • 0.2.6
    record
    2025-01-22 · diff ↗ ·
    added 2 exports
    ComputeTotalExpression, Summarize
  • R
    R 4.4.0 released · 2024-04-24
  • 0.2.5
    record
    2024-02-15 · diff ↗ ·
    added 4 exports
    ComputeColumnStatistics, GetPairContrasts, PoolColumns, ReadFeatureCounts
  • R
    R 4.3.0 released · 2023-04-21
  • 0.2.2
    record
    2023-04-20 · diff ↗ ·
    added 10 exports
    ComputeNonConstantParam, ComputeSummaryStatistics, Correct4sUDropoutHLFactor, Correct4sUDropoutHLSpline, Estimate4sUDropoutPercentage, Estimate4sUDropoutPercentageForSample, EvaluateNonConstantParam, SimulateTimeCourseNonConstant, f.nonconst, f.nonconst.linear
  • 0.2.1
    record
    2023-02-27 · diff ↗ ·
    removed 8 exports
    GetSparseMatrix, PlotToxicityTest, PlotToxicityTestAll, PlotToxicityTestDeferAll, PlotToxicityTestRank, PlotToxicityTestRankAll, PlotToxicityTestRankDeferAll, VersionString
    added 26 exports
    ComputePseudoNtr, CreatePdfs, CreatePdfsComparison, CreatePdfsParameters, CreatePdfsProfiles, DESeq2BIC, GetMatrix, IsSparse, Metadata, Pairwise, Plot4sUDropout, Plot4sUDropoutAll, Plot4sUDropoutDeferAll, Plot4sUDropoutRank, Plot4sUDropoutRankAll, Plot4sUDropoutRankDeferAll, ReadCounts, ReadNewTotal, RenameColumns, SaveNtrSlot, Semantics.concentration, SwapColumns, UpdateSymbols, UseNtrSlot, as.Seurat.grandR, merge.grandR
  • 0.2.0
    record
    2022-09-20
  • R
    R 4.2.0 released · 2022-04-22

Package metadata

First published
2022-09-20
Total releases
6 / 4 yrs
License
Apache License (>= 2)
Minimum R
≥ 3.5.0
Download size
646 KB

Cite

Cite this package

Run in R for the authors' entry:

citation("grandR")

The package provides a citation file, so citation() returns the authors' own entry.

It points to 10.1093/bioinformatics/bty256, 10.1038/s41586-019-1369-y, 10.1038/s41467-023-39163-4.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for grandR version 0.2.7 [Data set]. HJJB, LLC. Data release v2026-10-19. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-19, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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