Lipid Set Enrichment Analysis with Dual KS and 'fgsea' Engines
Overview
Provides biology-aware lipid set enrichment analysis (LSEA) for lipidomics data using dual engines: the Kolmogorov-Smirnov test and the fast gene set enrichment algorithm from the 'fgsea' package. Annotates lipids into biological groups at three levels (lipid class, LIPID MAPS category, functional category) and tests for coordinated directional shifts between conditions. Includes fatty acid chain analysis with trend plots weighted by lipid abundance (Spearman rank correlation, configurable smoothing), wide-format chain position output (sn-1, sn-2, sn-3, sn-4), annotation confidence filtering, and export utilities for reproducible reporting in CSV, 'Excel', and PDF formats. Vignettes are available in English and Spanish. Methods are based on Subramanian et al. (2005) doi:10.1073/pnas.0506580102 and Korotkevich et al. (2021) doi:10.1101/060012.
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK7 OK2026-06-17
Documentation
- Help pages
- 13
- Examples that run
- 100%6 run in a plain check
- Exported functions with examples
- 60%
- Documented parameters
- 100%
- Return-value docs
- 100%
- Help pages citing references
- 15%
Downloads
Repository
Stars over time
Releases over time
5 development-tooling and community-health practices detected across 4 families in the upstream repository
Checks run against github.com/davidgo464/easylsea on 2026-10-22.
The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel
Dependencies
Code & Tests
Datasets
People & History
- 0.2.1Latest2026-06-16 · current release
- RR 4.6.0 released · 2026-04-24
Package metadata
- First published
- 2026-06-16
- Total releases
- 1 / 1 yrs
- License
- MIT + file LICENSE OSI
- Minimum R
- ≥ 4.1.0
- Bundled data
- 4.0 KB / 1 file
- Download size
- 356 KB
Cite
Cite this package
Run in R for the authors' preferred citation:
citation("easyLSEA")This package has no citation file, so citation() returns this entry built from DESCRIPTION.
Cite the R Observatory
For a number measured here: a download total, a coverage figure, an archival date.
From data release v2026-10-24, which the citation names so these numbers can be found later. More on citing and the projects behind them.