Retrieve Reaction Rate Dynamics from Metabolite Concentration Time Courses
Overview
Reaction rate dynamics can be retrieved from metabolite concentration time courses. User has to provide corresponding stoichiometric matrix but not a regulation model (Michaelis-Menten or similar). Instead of solving an ordinary differential equation (ODE) system describing the evolution of concentrations, we use B-splines to catch the concentration and rate dynamics then solve a least square problem on their coefficients with non-negativity (and optionally monotonicity) constraints. Constraints can be also set on initial values of concentration. The package 'dynafluxr' can be used as a library but also as an application with command line interface dynafluxr::cli("-h") or graphical user interface dynafluxr::gui().
- corrections for public release on CRAN
From NEWS.md in the release
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK14 OK2026-03-10
Documentation
- Help pages
- 4
- Examples that run
- 100%1 run in a plain check
- Exported functions with examples
- 25%
- Documented parameters
- 83%
- Return-value docs
- 100%
- Help pages citing references
- 0%
- glyco HTML
Downloads
Dependencies
Code & Tests
People & History
- RR 4.6.0 released · 2026-04-24
- 1.0.1Latest2025-07-10 · current release
- RR 4.5.0 released · 2025-04-11
Package metadata
- First published
- 2025-07-10
- Total releases
- 1 / 1 yrs
- License
- GPL-2 OSI
- Download size
- 190 KB
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