dtpcrm
0.1.1Dose Transition Pathways for Continual Reassessment Method
Overview
Provides the dose transition pathways (DTP) to project in advance the doses recommended by a model-based design for subsequent patients (stay, escalate, deescalate or stop early) using all the accumulated toxicity information; See Yap et al (2017) <doi: 10.1158/1078-0432.CCR-17-0582>. DTP can be used as a design and an operational tool and can be displayed as a table or flow diagram. The 'dtpcrm' package also provides the modified continual reassessment method (CRM) and time-to-event CRM (TITE-CRM) with added practical considerations to allow stopping early when there is sufficient evidence that the lowest dose is too toxic and/or there is a sufficient number of patients dosed at the maximum tolerated dose.
Install
Health
- NOTE r-devel-linux-x86_64-debian-clang
- NOTE r-devel-linux-x86_64-debian-gcc
- NOTE r-devel-linux-x86_64-fedora-clang
- NOTE r-devel-linux-x86_64-fedora-gcc
- NOTE r-devel-windows-x86_64
- NOTE r-oldrel-macos-arm64
- NOTE r-oldrel-macos-x86_64
- NOTE r-oldrel-windows-x86_64
- NOTE r-patched-linux-x86_64
- NOTE r-release-linux-x86_64
- NOTE r-release-macos-arm64
- NOTE r-release-macos-x86_64
- NOTE r-release-windows-x86_64
- NOTE2026-03-100 OK · 14 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
Documentation
- Examples that run
- 100%
- Documented parameters
- 98%
- Return-value docs
- 54%
- References docs
- 46%
Downloads
Dependencies
Nothing depends on this yet.
Code & Tests
People & History
2 releases. Pick two to compare their code metrics. R releases are shown for context.
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- RR 4.1.0 released · 2021-05-18
- RR 4.0.0 released · 2020-04-24
- 0.1.1Latest
- RR 3.6.0 released · 2019-04-26
- 0.1.02019-04-10
- RR 3.5.0 released · 2018-04-23
Package metadata
- First published
- 2019-04-10
- Total releases
- 2 / 7 yrs
- License
- GPL (>= 2) OSI
- Download size
- 127 KB
- Installed size
- not tracked yet
- With dependencies
- not tracked yet
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