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dtpcrm

0.1.1

Dose Transition Pathways for Continual Reassessment Method

0packages depend
2.5Kdownloads / year
19.4%test coverage
0/13checks pass

Overview

About
Maintained by Christina YapFirst published 2019-04-102 releasesCRAN page ↗

Provides the dose transition pathways (DTP) to project in advance the doses recommended by a model-based design for subsequent patients (stay, escalate, deescalate or stop early) using all the accumulated toxicity information; See Yap et al (2017) <doi: 10.1158/1078-0432.CCR-17-0582>. DTP can be used as a design and an operational tool and can be displayed as a table or flow diagram. The 'dtpcrm' package also provides the modified continual reassessment method (CRM) and time-to-event CRM (TITE-CRM) with added practical considerations to allow stopping early when there is sufficient evidence that the lowest dose is too toxic and/or there is a sufficient number of patients dosed at the maximum tolerated dose.

Install

Health

CRAN checks
13NOTE
Failing flavors
  • NOTE r-devel-linux-x86_64-debian-clang
  • NOTE r-devel-linux-x86_64-debian-gcc
  • NOTE r-devel-linux-x86_64-fedora-clang
  • NOTE r-devel-linux-x86_64-fedora-gcc
  • NOTE r-devel-windows-x86_64
  • NOTE r-oldrel-macos-arm64
  • NOTE r-oldrel-macos-x86_64
  • NOTE r-oldrel-windows-x86_64
  • NOTE r-patched-linux-x86_64
  • NOTE r-release-linux-x86_64
  • NOTE r-release-macos-arm64
  • NOTE r-release-macos-x86_64
  • NOTE r-release-windows-x86_64
Slowest check: 2.1 min · r-oldrel-windows-x86_64
Code health
Yes
Tests · ratio 0.41
19.4%
Coverage · measured lines
100%
Documentation · exports
2
Dependencies · direct
Check history
  • NOTE2026-03-10
    0 OK · 14 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

Documentation
READMENoVignettesYes · dynamicpkgdown siteNoNEWSNoCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
98%
Return-value docs
54%
References docs
46%

Downloads

2.5K
CRAN downloads in the past year
Rank #21,302 · ~7/day · ~206/mo
Daily download trend is not available in this view yet.
13230 days
52190 days
2.5K1 year
Compare downloads with other packages →
Also on95 r2u18 autocran

Dependencies

Declared dependencies
5 external dependencies (excludes base and recommended)
Depends (0)
none
Imports (2)
LinkingTo (0)
none
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Code & Tests

People & History

People (4)
Maintainer (1)
Author, Maintainer
Authors (4)
Author, Maintainer
Author
Package Timeline

2 releases. Pick two to compare their code metrics. R releases are shown for context.

  • R
    R 4.6.0 released · 2026-04-24
  • R
    R 4.5.0 released · 2025-04-11
  • R
    R 4.4.0 released · 2024-04-24
  • R
    R 4.3.0 released · 2023-04-21
  • R
    R 4.2.0 released · 2022-04-22
  • R
    R 4.1.0 released · 2021-05-18
  • R
    R 4.0.0 released · 2020-04-24
  • 0.1.1Latest
    2019-08-20 · current release · diff ↗
  • R
    R 3.6.0 released · 2019-04-26
  • 0.1.0
    2019-04-10
  • R
    R 3.5.0 released · 2018-04-23

Package metadata

First published
2019-04-10
Total releases
2 / 7 yrs
License
GPL (>= 2) OSI
Download size
127 KB
Installed size
not tracked yet
With dependencies
not tracked yet

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("dtpcrm")
Yap, C., Brock, K., Pan, Y., & Slade, D. (2019). dtpcrm: Dose Transition Pathways for Continual Reassessment Method (Version 0.1.1) [Computer software]. https://doi.org/10.32614/CRAN.package.dtpcrm

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for dtpcrm version 0.1.1 [Data set]. HJJB, LLC. Data release v2026-08-22. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-22, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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