R Observatory: Metrics for drugdevelopR version 1.0.2

Balamuta, James Joseph

doi:10.5281/zenodo.21843040

drugdevelopR

1.0.2Package record

Utility-Based Optimal Phase II/III Drug Development Planning

0packages depend

3.3Kdownloads / year

–test coverage

13/13flavors OK

Overview

About

Maintained by Lukas D. SauerCRAN page ↗GitHub ↗Website ↗Issues ↗

Plan optimal sample size allocation and go/no-go decision rules for phase II/III drug development programs with time-to-event, binary or normally distributed endpoints when assuming fixed treatment effects or a prior distribution for the treatment effect, using methods from Kirchner et al. (2016) doi:10.1002/sim.6624 and Preussler (2020). Optimal is in the sense of maximal expected utility, where the utility is a function taking into account the expected cost and benefit of the program. It is possible to extend to more complex settings with bias correction (Preussler S et al. (2020) doi:10.1186/s12874-020-01093-w), multiple phase III trials (Preussler et al. (2019) doi:10.1002/bimj.201700241), multi-arm trials (Preussler et al. (2019) doi:10.1080/19466315.2019.1702092), and multiple endpoints (Kieser et al. (2018) doi:10.1002/pst.1861).

Changes in 1.0.2

Improvements that will work with the Shiny apps:

Adding trace to all optimal_*() functions.

From NEWS.md in the release

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("drugdevelopR", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("Sterniii3/drugdevelopR")

Development version from Sterniii3/drugdevelopR. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-drugdevelopr

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled. We list this channel from recorded r2u download activity rather than from a live index of the repository, so treat it as last known rather than guaranteed.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-drugdevelopR

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-drugdevelopR

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed). We list this channel from recorded autoCRAN download activity rather than from a live index of the repository, so treat it as last known rather than guaranteed.

Health

CRAN checks

13OK

CRAN check page ↗

Slowest check: 11.0 min · r-oldrel-windows-x86_64

Status changes

OK13 OK2026-08-05
NOTE12 OK, 1 NOTE2026-08-01
OK14 OK2026-03-10

Advisories

none known

How this is measured·How advisories are found

Documentation

In release 1.0.2

READMEYes · 341 wordsVignettesYes · 11 · dynamicNEWSYes · 100% structured · mentions 1.0.2Citation fileNoWebsiteYes · pkgdown

Help pages: 92 (78 internal)includes a package overview page
Examples that run: 62%39 run in a plain check · 24 only when donttest examples are enabled (R CMD check --as-cran)
Exported functions with examples: 79%
Documented parameters: 100%
Return-value docs: 99%
Help pages citing references: 16%

Vignettes (11)

Show 1 moreHide 1 vignette

Time-to-event outcome variables HTML

How these are measured

Downloads

3.3K

CRAN downloads in the past year

Rank #12,242 · ~9/day · ~273/mo

Releases R versions

Daily download trend is not available in this view yet.

34630 days

89190 days

3.3K1 year

Compare downloads with other packages →

Also on92 r2u7 autocran

How downloads are counted

Repository

sterniii3/drugdevelopr ↗Account: Sterniii3

3Stars

3Forks

0Open issues

0Open PRs

6Releases

749Commits

5Commit identities

r-package

749 commits · Last activity 2025-01-14 · 0% stars, 30d

Responsiveness

How these are sampled

PRs merged (all time): 100%
Median days to close, 50 most recently updated closed issues: not measured
Median days to close, 50 most recently updated closed PRs: 0

Stars over time

2024-06-03 · 32026-07-07 · 3

How these are measured

PracticesBeta

8 development-tooling and community-health practices detected across 4 families in the upstream repository

Checks run against github.com/sterniii3/drugdevelopr on 2026-10-11.

Continuous integration (2)

GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux

Docs source (4)

README.Rmdpkgdown

GitHub Pages site last deployed 2025-01-14 · The repository has a site deploy workflow

pkgdown site last built 2025-01-14

Coverage (1)

Coverage reporting (Codecov)

Lint, format, editor (1)

RStudio project

How this is detected·Detection ruleset v3 (2026-09-26)

Dependencies

Declared dependencies

14 external dependencies (excludes base and recommended)

Installing drugdevelopR adds 20 packages (12 with compiled code, 12 MB of source tarballs). Heaviest: cubature 3.2 MB, Rcpp 1.8 MB, mvtnorm 1.0 MB.

Depends (5)

R >= 3.5.0doParallelparallelforeach iterators

Imports (6)

mvtnorm cubature msmMASSstatsprogressr

LinkingTo (0)

none

Suggests (7)

rmarkdown knitr testthat covr kableExtra magrittr devtools

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

How these are counted

Code & Tests

People & History

People (5)

Lukas D. Sauer

Author, Maintainer since 1.0.1 (2024)

Author

Author

Author

Author

Releases (2)

Pick two releases to compare their code metrics.

R
R 4.6.0 released · 2026-04-24
R
R 4.5.0 released · 2025-04-11
1.0.2Latest
record
2025-01-14 · current release · diff ↗
R
R 4.4.0 released · 2024-04-24
1.0.1
record
2024-01-10
R
R 4.3.0 released · 2023-04-21

Package metadata

First published: 2024-01-10
Total releases: 2 / 2 yrs
License: MIT + file LICENSE OSI
Minimum R: ≥ 3.5.0
Download size: 284 KB

Appears in task views

Clinical Trial Design, Monitoring, Analysis and Reporting

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("drugdevelopR")

Format

Sauer, L. D., Cepicka, J., Erdmann, S., Kieser, M., & Kirchner, M. (2025). drugdevelopR: Utility-Based Optimal Phase II/III Drug Development Planning (Version 1.0.2) [Computer software]. https://doi.org/10.32614/CRAN.package.drugdevelopR

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

Format

APA

Balamuta, J. J. (2026). R Observatory: Metrics for drugdevelopR version 1.0.2 [Data set]. HJJB, LLC. Data release v2026-10-18. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-18, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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