R Observatory: Metrics for drugdevelopR version 1.0.2

Balamuta, James Joseph

doi:10.5281/zenodo.21843040

drugdevelopR

1.0.2

Utility-Based Optimal Phase II/III Drug Development Planning

0packages depend

3Kdownloads / year

–test coverage

13/13checks pass

Overview

About

Maintained by Lukas D. SauerFirst published 2024-01-102 releasesCRAN page ↗GitHub ↗

Plan optimal sample size allocation and go/no-go decision rules for phase II/III drug development programs with time-to-event, binary or normally distributed endpoints when assuming fixed treatment effects or a prior distribution for the treatment effect, using methods from Kirchner et al. (2016) doi:10.1002/sim.6624 and Preussler (2020). Optimal is in the sense of maximal expected utility, where the utility is a function taking into account the expected cost and benefit of the program. It is possible to extend to more complex settings with bias correction (Preussler S et al. (2020) doi:10.1186/s12874-020-01093-w), multiple phase III trials (Preussler et al. (2019) doi:10.1002/bimj.201700241), multi-arm trials (Preussler et al. (2019) doi:10.1080/19466315.2019.1702092), and multiple endpoints (Kieser et al. (2018) doi:10.1002/pst.1861).

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("drugdevelopR", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("Sterniii3/drugdevelopR")

Development version from Sterniii3/drugdevelopR. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-drugdevelopr

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-drugdevelopR

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-drugdevelopR

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed).

Health

CRAN checks

13OK

Slowest check: 11.1 min · r-oldrel-windows-x86_64

Code health

Yes

Tests · ratio 0.13

not tracked

Coverage

100%

Documentation · exports

10

Dependencies · direct

Check history

OK2026-08-05
13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
NOTE2026-08-01
12 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
OK2026-03-10
14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

READMEYes · 341 wordsVignettesYes · dynamicpkgdown siteNoNEWSYes · 100% structuredCode of conductNoContributing guideNo

Examples that run: 89%
Documented parameters: 100%
Return-value docs: 99%
References docs: 16%

Downloads

3K

CRAN downloads in the past year

Rank #15,710 · ~8/day · ~247/mo

Releases R versions

Daily download trend is not available in this view yet.

21430 days

67190 days

3K1 year

Compare downloads with other packages →

Also on121 r2u16 autocran

Repository

GitHub ↗ sterniii3/drugdevelopr

3Stars

3Forks

0Open issues

0Open PRs

6Releases

749Commits

5Contributors

r-package

749 commits · Last activity 2025-01-14

Stars over time

2024-06-03 · 32026-07-07 · 3

Repository practices

Upstream repositoryBeta

4 development-tooling and community-health practices detected across 4 families in the upstream repository

Checks run against github.com/sterniii3/drugdevelopr on 2026-08-09.

Continuous integration (1)

GitHub Actions

Docs source (1)

README.Rmd

Lint, format, editor (1)

RStudio project

Coverage (1)

Codecov

How this is detected·Detection ruleset v1 (2026-07-18)

Dependencies

Declared dependencies

14 external dependencies (excludes base and recommended)

Depends (5)

R >= 3.5.0doParallelparallelforeach iterators

Imports (6)

mvtnorm cubature msmMASSstatsprogressr

LinkingTo (0)

none

Suggests (7)

rmarkdown knitr testthat covr kableExtra magrittr devtools

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

Code & Tests

People & History

People (5)

Maintainer (1)

Lukas D. Sauer

Author, Maintainer

Authors (5)

Author, Maintainer

Author

Author

Author

Author

Package Timeline

2 releases. Pick two to compare their code metrics. R releases are shown for context.

R
R 4.6.0 released · 2026-04-24
R
R 4.5.0 released · 2025-04-11
1.0.2Latest
2025-01-14 · current release · diff ↗
R
R 4.4.0 released · 2024-04-24
1.0.1
2024-01-10
R
R 4.3.0 released · 2023-04-21

Package metadata

First published: 2024-01-10
Total releases: 2 / 2 yrs
License: MIT + file LICENSE OSI
Minimum R: ≥ 3.5.0
Download size: 284 KB
Installed size: not tracked yet
With dependencies: not tracked yet

Appears in task views

Clinical Trial Design, Monitoring, Analysis and Reporting

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("drugdevelopR")

Format

Sauer, L. D., Cepicka, J., Erdmann, S., Kieser, M., & Kirchner, M. (2025). drugdevelopR: Utility-Based Optimal Phase II/III Drug Development Planning (Version 1.0.2) [Computer software]. https://doi.org/10.32614/CRAN.package.drugdevelopR

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

Format

APA

Balamuta, J. J. (2026). R Observatory: Metrics for drugdevelopR version 1.0.2 [Data set]. HJJB, LLC. Data release v2026-08-15. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-15, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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