Integrative Analysis of Omics Data in Terms of Network, Evolution and Ontology
Overview
The focus of the dnet by Fang and Gough (2014) doi:10.1186/s13073-014-0064-8 is to make sense of omics data (such as gene expression and mutations) from different angles including: integration with molecular networks, enrichments using ontologies, and relevance to gene evolutionary ages. Integration is achieved to identify a gene subnetwork from the whole gene network whose nodes/genes are labelled with informative data (such as the significant levels of differential expression or survival risks). To help make sense of identified gene networks, enrichment analysis is also supported using a wide variety of pre-compiled ontologies and phylostratific gene age information in major organisms including: human, mouse, rat, chicken, C.elegans, fruit fly, zebrafish and arabidopsis. Add-on functionalities are supports for calculating semantic similarity between ontology terms (and between genes) and for calculating network affinity based on random walk; both can be done via high-performance parallel computing.
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Documentation
- Help pages
- 43
- Examples that run
- 44%19 run in a plain check · 16 never run · 8 hold no code
- Exported functions with examples
- 100%
- Documented parameters
- 94%
- Return-value docs
- 100%
- Help pages citing references
- 5%
Downloads
Dependencies
Code & Tests
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People & History
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- RR 4.4.0 released · 2024-04-24
- archivedRemoved from CRAN2024-01-30email to the maintainer is undeliverable
- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- RR 4.1.0 released · 2021-05-18
- RR 4.0.0 released · 2020-04-24
- 1.1.72020-02-20 · diff ↗
- 1.1.62020-01-23 · diff ↗
- 1.1.52019-10-18 · diff ↗
- RR 3.6.0 released · 2019-04-26
- 1.1.42018-08-10 · diff ↗
- RR 3.5.0 released · 2018-04-23
- 1.1.32018-02-23 · diff ↗
- 1.1.22018-01-19 · diff ↗
- 1.1.12017-07-09 · diff ↗
- RR 3.4.0 released · 2017-04-21
Show 16 earlier eventsHide 16 earlier events
- 1.0.102017-01-27 · diff ↗
- 1.0.92016-05-31 · diff ↗
- RR 3.3.0 released · 2016-05-03
- 1.0.82016-04-01 · diff ↗
- 1.0.7
- RR 3.2.0 released · 2015-04-16
- 1.0.62014-09-17 · diff ↗
- 1.0.52014-07-02 · diff ↗
- 1.0.42014-06-05 · diff ↗
- 1.0.32014-05-19 · diff ↗ ·
added 6 exports
dCheckParallel, dDAGancestor, dDAGgeneSim, dDAGtermSim, dRWRcontact, dRWRpipeline - 1.0.2
- 1.0.12014-04-21 · diff ↗ ·
removed 5 exports
visColoralpha, visColormap, visHeatmap, visHeatmapAdv, visTreeBootstrapadded 1 export
visBoxplotAdv - RR 3.1.0 released · 2014-04-10
- 1.0.02014-04-09 · diff ↗ ·
added 8 exports
dDAGannotate, dDAGinduce, dDAGlevel, dDAGreverse, dDAGroot, dDAGtip, dEnricher, visDAG - 0.99.02014-03-25
- RR 3.0.0 released · 2013-04-03
Package metadata
- First published
- 2014-03-25
- Total releases
- 19 / 12 yrs
- License
- GPL-2 OSI
- Minimum R
- ≥ 3.1.0
- Bundled data
- 396 KB / 3 files
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citation("dnet")The package provides a citation file, so citation() returns the authors' own entry.
It points to 10.1186/s13073-014-0064-8.
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