Calibration, Validation, and Simulation of TKTD Models
Overview
Eases the use of ecotoxicological effect models. Can simulate common toxicokinetic-toxicodynamic (TK/TD) models such as General Unified Threshold models of Survival (GUTS) and Lemna. It can derive effects and effect profiles (EPx) from scenarios. It supports the use of 'tidyr' workflows employing the pipe symbol. Time-consuming tasks can be parallelized.
- MODIFIED
- Minor fix to HTML elements in man pages.
From NEWS.md in the release
Install
Health
- OK13 OK2026-09-09
- ERROR12 OK, 1 ERROR2026-09-04
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-06-09
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- ERROR12 OK, 1 ERROR2026-06-08
- OK14 OK2026-03-10
Documentation
- Help pages
- 97 (1 internal)
- Examples that run
- 98%49 run in a plain check · 1 only when donttest examples are enabled (R CMD check --as-cran)
- Exported functions with examples
- 60%
- Documented parameters
- 100%
- Return-value docs
- 97%
- Help pages citing references
- 26%
Downloads
Repository
- PRs merged (all time)
- 0%
- Median days to close, 50 most recently updated closed issues
- not measured
- Median days to close, 50 most recently updated closed PRs
- 82
Stars over time
Forks over time
PRs over time
10 development-tooling and community-health practices detected across 7 families in the upstream repository
Checks run against github.com/cvasi-tktd/cvasi on 2026-10-25.
The R CMD check workflow runs on Linux, macOS and Windows, and on R-devel
GitHub Pages site last deployed 2024-11-22
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Dependencies
Code & Tests
Datasets
People & History
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- 1.5.1Latest
- 1.5.02025-09-11 · diff ↗ ·
added 17 exports
GUTS_SD, Magma, SamX, ci_from_hessian, diagnostics, fit_growth, fit_tktd, get_param, get_times, is_deb, is_guts, is_guts_it, is_guts_sd, is_lemna, num_info, td2cs, tox_data - RR 4.5.0 released · 2025-04-11
- 1.4.0
- 1.3.1
- 1.2.02024-09-23 · diff ↗ ·
added 7 exports
DEBtox, explore_space, lik_profile, log_lik, plot_lik_profile, plot_param_space, set_bounds - 1.1.3
- unarchivedReturned to CRAN2024-05-30
- 1.1.0
- archivedRemoved from CRAN2024-05-14NO issues were addressed on re-submission
- 0.10.52024-05-04 · diff ↗
- 0.10.42024-05-02
- RR 4.4.0 released · 2024-04-24
Package metadata
- First published
- 2024-05-02
- Total releases
- 9 / 2 yrs
- License
- GPL (>= 3) OSI
- Minimum R
- ≥ 3.5.0
- Bundled data
- 55 KB / 11 files
- Download size
- 663 KB
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