R Observatory: Metrics for clinDR version 2.5.3

Balamuta, James Joseph

doi:10.5281/zenodo.21843040

clinDR

2.5.3Package record

Simulation and Analysis Tools for Clinical Dose Response Modeling

1packages dependsuggested by 1

4Kdownloads / year

–test coverage

13/13flavors OK

Overview

About

Maintained by Neal ThomasCRAN page ↗

Bayesian and ML Emax model fitting, graphics and simulation for clinical dose response. The summary data from the dose response meta-analyses in Thomas, Sweeney, and Somayaji (2014) doi:10.1080/19466315.2014.924876 and Thomas and Roy (2016) doi:10.1080/19466315.2016.1256229 Wu, Banerjee, Jin, Menon, Martin, and Heatherington(2017) doi:10.1177/0962280216684528 are included in the package. The prior distributions for the Bayesian analyses default to the posterior predictive distributions derived from these references.

Install

R (CRAN)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("clinDR", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-clindr

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled. We list this channel from recorded r2u download activity rather than from a live index of the repository, so treat it as last known rather than guaranteed.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-clinDR

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-clinDR

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed). We list this channel from recorded autoCRAN download activity rather than from a live index of the repository, so treat it as last known rather than guaranteed.

Health

CRAN checks

13OK

CRAN check page ↗

Slowest check: 4.2 min · r-oldrel-windows-x86_64

Status changes

OK13 OK2026-08-05
NOTE12 OK, 1 NOTE2026-08-01
OK14 OK2026-03-10

Advisories

none known

How this is measured·How advisories are found

Documentation

In release 2.5.3

READMENoVignettesYes · 3 · staticNEWSYes · 33% structuredCitation fileNoWebsitenot declared in DESCRIPTION

Help pages: 64includes a package overview page
Examples that run: 33%18 run in a plain check (1 of them under a condition) · 36 never run
Exported functions with examples: 85%
Documented parameters: 80%
Return-value docs: 83%
Help pages citing references: 14%

Vignettes (3)

How these are measured

Downloads

4K

CRAN downloads in the past year

Rank #6,650 · ~11/day · ~332/mo

Releases R versions

Daily download trend is not available in this view yet.

56730 days

1.3K90 days

4K1 year

Compare downloads with other packages →

Also on123 r2u13 autocran33 c2d4u

How downloads are counted

Dependencies

Declared dependencies

16 external dependencies (excludes base and recommended)

Installing clinDR adds 92 packages (53 with compiled code, 87 MB of source tarballs). Heaviest: BH 14 MB, stringi 11 MB, ggplot2 6.0 MB.

Depends (3)

R >= 3.5.0rstan shiny

Imports (16)

foreachgraphicsDoseFindingstatsmvtnormutilsparalleldoParallel ggplot2 tidyr purrr tibble dplyr glue waiter officer

LinkingTo (0)

none

Suggests (2)

knitr rmarkdown

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

1direct

0indirect

Depends 1

Suggested by 1

Depends, Imports or LinkingTo, most downloaded first

ememax

Suggests, most downloaded first

BayesianMCPMod

How these are counted

Code & Tests

Datasets

People & History

People (5)

Neal Thomas

Author, Maintainer since 1.6 (2017)

Budhaditya Goswami

Author · added in 2.5.3

Satrajit Roychoudhury

Author · added in 2.5.3

Mike K. Smith

Author · added in 2.3.5

Jing Wu

Author

Releases (10)

Pick two releases to compare their code metrics.

2.5.3Latest
record
2026-09-21 · current release · diff ↗
R
R 4.6.0 released · 2026-04-24
2.5.2
record
2025-10-02 · diff ↗
R
R 4.5.0 released · 2025-04-11
R
R 4.4.0 released · 2024-04-24
2.4.1
record
2023-08-09 · diff ↗ ·
removed 1 export
runShiny

added 4 exports
print.emaxPrior, randomEmax, bpchkMonoEmax, runSimulations
R
R 4.3.0 released · 2023-04-21
R
R 4.2.0 released · 2022-04-22
R
R 4.1.0 released · 2021-05-18
2.3.5
record
2021-04-12 · diff ↗ ·
added 1 export
runShiny
2.3
record
2020-07-01 · diff ↗
R
R 4.0.0 released · 2020-04-24
2.2.1
record
2019-12-17 · diff ↗ ·
added 3 exports
emaxPrior.control, solveDose, solveEmax
R
R 3.6.0 released · 2019-04-26
1.9
record
2019-01-04 · diff ↗ ·
added 1 export
showStanModels
1.8
record
2018-05-05 · diff ↗ ·
added 11 exports
coef.emaxsimB, coef.emaxsim, sigma.emaxsimB, sigma.emaxsim, vcov.emaxsim, predict.emaxsimB, coef.fitEmax, sigma.fitEmax, vcov.fitEmax, coef.fitEmaxB, sigma.fitEmaxB

Show 4 earlier eventsHide 4 earlier events

R
R 3.5.0 released · 2018-04-23
1.7
record
2018-02-19 · diff ↗
1.6
record
2017-12-04
R
R 3.4.0 released · 2017-04-21

Package metadata

First published: 2017-12-04
Total releases: 10 / 9 yrs
License: GPL (>= 2) OSI
Minimum R: ≥ 3.5.0
Bundled data: 78 KB / 1 file
Download size: 2.3 MB

Appears in task views

Analysis of Pharmacokinetic Data

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("clinDR")

Format

Thomas, N., Goswami, B., Roychoudhury, S., Smith, M. K., & Wu, J. (2026). clinDR: Simulation and Analysis Tools for Clinical Dose Response Modeling (Version 2.5.3) [Computer software]. https://doi.org/10.32614/CRAN.package.clinDR

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

Format

APA

Balamuta, J. J. (2026). R Observatory: Metrics for clinDR version 2.5.3 [Data set]. HJJB, LLC. Data release v2026-10-23. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-23, which the citation names so these numbers can be found later. More on citing and the projects behind them.

Report a problem with this page →