Analyze Multiple Exposure Realizations in Association Studies
Overview
Analyze association studies with multiple realizations of a noisy or uncertain exposure. These can be obtained from e.g. a two-dimensional Monte Carlo dosimetry system (Simon et al 2015 doi:10.1667/RR13729.1) to characterize exposure uncertainty. The implemented methods are regression calibration (Carroll et al. 2006 doi:10.1201/9781420010138), extended regression calibration (Little et al. 2023 doi:10.1038/s41598-023-42283-y), Monte Carlo maximum likelihood (Stayner et al. 2007 doi:10.1667/RR0677.1), frequentist model averaging (Kwon et al. 2023 doi:10.1371/journal.pone.0290498), and Bayesian model averaging (Kwon et al. 2016 doi:10.1002/sim.6635). Supported model families are Gaussian, binomial, multinomial, Poisson, proportional hazards, and conditional logistic.
Bug fixes
- Fixed a BMA error when fitting models with a single formula-based effect modifier.
- Fixed numerical failures that could occur while fitting subgroup-coded effect modifiers, despite valid transformed subgroup effects.
- FMA now honors the optimizer selected through
optim.method.
Changes
- Newly fitted method results no longer contain the redundant
runtimefield. Fitting, confidence interval, and total computation times remain available throughtiming. Fitted objects from earlier versions that contain onlyruntimeremain supported.
From NEWS.md in the release
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-06-09
- ERROR12 OK, 1 ERROR2026-06-08
- OK12 OK2026-04-25
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- NOTE11 OK, 2 NOTE2026-04-22
- ERROR10 OK, 2 NOTE, 1 ERROR2026-04-18
- NOTE5 OK, 2 NOTE2026-03-30
Documentation
- Help pages
- 19includes a package overview page
- Examples that run
- 50%9 run in a plain check · 9 only when donttest examples are enabled (R CMD check --as-cran)
- Exported functions with examples
- 100%
- Documented parameters
- 87%
- Return-value docs
- 91%
- Help pages citing references
- 16%
Downloads
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Dependencies
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- RR 4.6.0 released · 2026-04-24
- 0.2.0
- 0.1.12026-03-29
- RR 4.5.0 released · 2025-04-11
Package metadata
- First published
- 2026-03-29
- Total releases
- 6 / 1 yrs
- License
- MIT + file LICENSE OSI
- Minimum R
- ≥ 4.1.0
- Bundled data
- 263 KB / 1 file
- Download size
- 1.3 MB
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