Analysis of Sex Differences in Omics Data for Complex Diseases
Overview
Tools to analyze sex differences in omics data for complex diseases. It includes functions for differential expression analysis using the 'limma' method doi:10.1093/nar/gkv007, interaction testing between sex and disease, pathway enrichment with 'clusterProfiler' doi:10.1089/omi.2011.0118, and gene regulatory network (GRN) construction and analysis using 'igraph'. The package enables a reproducible workflow from raw data processing to biological interpretation.
Install
Health
- OK13 OK2026-09-08
- ERROR12 OK, 1 ERROR2026-09-07
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-07-31
- OK13 OK2026-06-27
Show 5 earlier changesHide 5 earlier changes
- ERROR12 OK, 1 ERROR2026-06-21
- OK13 OK2026-06-09
- ERROR12 OK, 1 ERROR2026-06-08
- OK13 OK2026-05-14
- ERROR11 OK, 1 NOTE, 2 ERROR2026-03-10
Documentation
- Help pages
- 25 (2 internal)includes a package overview page
- Examples that run
- 100%1 run in a plain check
- Exported functions with examples
- 4%
- Documented parameters
- 100%
- Return-value docs
- 100%
- Help pages citing references
- 4%
Downloads
Dependencies
Installing XYomics adds 142 packages (87 with compiled code, 138 MB of source tarballs). Heaviest: BH 14 MB, stringi 11 MB, ggplot2 6.0 MB. 6 more not on CRAN are not measured.
Code & Tests
Datasets
People & History
Pick two releases to compare their code metrics.
- 0.1.5Latest
- 0.1.42026-05-11 · diff ↗ ·
removed 8 exports
categorize_sex_sc, categorized_enrich_sc, convertdf2enr, generate_boxplot, generate_report, identify_sex_specific_genes, improved_pathway_enrichment, visualize_networkadded 14 exports
categorize_sex, categorized_enrich, convert_gene_ids, generate_dotplot_sc, generate_violinplot_bulk, get_top_hubs, plot_enrichment_dotplots, plot_network_pipeline, plot_volcano_deg, ppi_pipeline, sex_interaction_pipeline_sc, sex_stratified_pipeline_sc, validate_input_bulk, validate_input_sc - RR 4.6.0 released · 2026-04-24
- 0.1.32026-01-08 · diff ↗
- 0.1.22025-12-15 · diff ↗
- 0.1.12025-11-13
- RR 4.5.0 released · 2025-04-11
Package metadata
- First published
- 2025-11-13
- Total releases
- 5 / 1 yrs
- License
- MIT + file LICENSE OSI
- Minimum R
- ≥ 3.6
- Download size
- 4.9 MB
Cite
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Run in R for the authors' preferred citation:
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