Simulating Triad Genomewide Genotypes
Overview
Simulate genotypes for case-parent triads, case-control, and quantitative trait samples with realistic linkage diequilibrium structure and allele frequency distribution. For studies of epistasis one can simulate models that involve specific SNPs at specific sets of loci, which we will refer to as "pathways". TriadSim generates genotype data by resampling triad genotypes from existing data. The details of the method is described in the manuscript under preparation "Simulating Autosomal Genotypes with Realistic Linkage Disequilibrium and a Spiked in Genetic Effect" Shi, M., Umbach, D.M., Wise A.S., Weinberg, C.R.
- Important update on some key functions.
- Fix a bug.
From NEWS.md in the release
Install
Health
ERRORpackage dependenciesr-oldrel-macos-arm64
Package required but not available: ‘snpStats’ See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’ manual.
- ERROR12 OK, 1 ERRORNow
- ERROR12 OK, 2 ERROR2026-03-10
Documentation
- Help pages
- 8
- Examples that run
- 100%6 run in a plain check
- Exported functions with examples
- 100%
- Documented parameters
- 100%
- Return-value docs
- 100%
- Help pages citing references
- 0%
- TriadSim Vignette HTML
Downloads
Dependencies
Installing TriadSim adds 3 packages (0 with compiled code, 541 KB of source tarballs). Heaviest: iterators 293 KB, doParallel 160 KB, foreach 88 KB. 1 more not on CRAN is not measured.
Code & Tests
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- RR 4.6.0 released · 2026-04-24
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- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- 0.3.02021-09-08 · diff ↗
- RR 4.1.0 released · 2021-05-18
- unarchivedReturned to CRAN2020-07-12
- 0.2.02020-07-12 · diff ↗
- archivedRemoved from CRAN2020-07-07the request of the maintainer
- RR 4.0.0 released · 2020-04-24
- RR 3.6.0 released · 2019-04-26
- RR 3.5.0 released · 2018-04-23
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- RR 3.4.0 released · 2017-04-21
Package metadata
- First published
- 2017-05-13
- Total releases
- 5 / 9 yrs
- License
- GPL-3 OSI
- Minimum R
- ≥ 3.2.2
- Bundled data
- 16 KB / 2 files
- Download size
- 705 KB
Cite
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