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SimuRg

Building, Fitting and Evaluating PK/PD Modeles

v0.2.0 · May 19, 2026 · MIT + file LICENSE

Description

Provides a unified workflow for building, fitting using external engines, and evaluating ordinary differential equation (ODE)-based pharmacokinetic/pharmacodynamic (PK/PD) models. Supports generation of estimation scenarios and control files for external engines (e.g., 'Monolix'), simulation of models using 'rxode2', and creation of goodness-of-fit diagnostics. Includes tools for covariate modeling, virtual population design, and local and global sensitivity analyses.

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CRAN Check Status

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r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK

Check History

OK 13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Jun 9, 2026
ERROR 12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Jun 8, 2026
ERROR r-devel-linux-x86_64-debian-gcc

package dependencies

Packages required but not available: 'recipes', 'synthpop'

Package suggested but not available for checking: ‘GGally’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
OK 7 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE May 20, 2026

Dependency Network

Dependencies Reverse dependencies cluster dplyr fastDummies forcats ggplot2 jsonlite MASS philentropy purrr readr recipes rlang rxode2 scales stringr +10 more dependencies SimuRg

Version History

1 tracked
new 0.2.0 May 19, 2026