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SimDissolution

0.1.0

Modeling and Assessing Similarity of Drug Dissolutions Profiles

0packages depend
2.1Kdownloads / year
test coverage
11/13checks pass

Overview

About
Maintained by Kathrin MoellenhoffFirst published 2019-09-271 releasesCRAN page ↗

Implementation of a model-based bootstrap approach for testing whether two formulations are similar. The package provides a function for fitting a pharmacokinetic model to time-concentration data and comparing the results for all five candidate models regarding the Residual Sum of Squares (RSS). The candidate set contains a First order, Hixson-Crowell, Higuchi, Weibull and a logistic model. The assessment of similarity implemented in this package is performed regarding the maximum deviation of the profiles. See Moellenhoff et al. (2018) doi:10.1002/sim.7689 for details.

Install

Health

CRAN checks
2NOTE11OK
Failing flavors
  • NOTE r-devel-linux-x86_64-debian-clang
  • NOTE r-devel-linux-x86_64-debian-gcc
Slowest check: 1.3 min · r-oldrel-windows-x86_64
Code health
None
Tests · ratio 0.00
not tracked
Coverage
100%
Documentation · exports
4
Dependencies · direct
Check history
  • NOTE2026-03-10
    12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

Documentation
READMENoVignettesNopkgdown siteNoNEWSNoCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
44%
Return-value docs
100%
References docs
75%

Downloads

2.1K
CRAN downloads in the past year
Rank #19,519 · ~6/day · ~178/mo
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15430 days
58490 days
2.1K1 year
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Also on101 r2u21 autocran

Dependencies

Declared dependencies
3 external dependencies (excludes base and recommended)
Depends (4)
Imports (0)
none
LinkingTo (0)
none
Suggests (0)
none
Enhances (0)
none
Reverse dependencies
0direct
0indirect

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Code & Tests

Datasets

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Listed in earlier versions (1)
no longer listed · 0.1.0
Package Timeline

1 release. R releases are shown for context.

  • R
    R 4.6.0 released · 2026-04-24
  • 0.1.0Latest
    2026-03-10 · current release
  • R
    R 4.5.0 released · 2025-04-11

Package metadata

First published
2019-09-27
Total releases
1 / 7 yrs
License
GPL (>= 2) OSI
Bundled data
0.4 KB / 1 file
Download size
6.6 KB
Installed size
not tracked yet
With dependencies
not tracked yet

Cite

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Run in R for the authors' preferred citation:

citation("SimDissolution")

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APA

Balamuta, J. J. (2026). R Observatory: Metrics for SimDissolution version 0.1.0 [Data set]. HJJB, LLC. Data release v2026-08-26. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-26, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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