SimDissolution
0.1.0Modeling and Assessing Similarity of Drug Dissolutions Profiles
Overview
Implementation of a model-based bootstrap approach for testing whether two formulations are similar. The package provides a function for fitting a pharmacokinetic model to time-concentration data and comparing the results for all five candidate models regarding the Residual Sum of Squares (RSS). The candidate set contains a First order, Hixson-Crowell, Higuchi, Weibull and a logistic model. The assessment of similarity implemented in this package is performed regarding the maximum deviation of the profiles. See Moellenhoff et al. (2018) doi:10.1002/sim.7689 for details.
Install
Health
- NOTE r-devel-linux-x86_64-debian-clang
- NOTE r-devel-linux-x86_64-debian-gcc
- NOTE2026-03-1012 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
Documentation
- Examples that run
- 100%
- Documented parameters
- 44%
- Return-value docs
- 100%
- References docs
- 75%
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Code & Tests
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1 release. R releases are shown for context.
- RR 4.6.0 released · 2026-04-24
- 0.1.0Latest2026-03-10 · current release
- RR 4.5.0 released · 2025-04-11
Package metadata
- First published
- 2019-09-27
- Total releases
- 1 / 7 yrs
- License
- GPL (>= 2) OSI
- Bundled data
- 0.4 KB / 1 file
- Download size
- 6.6 KB
- Installed size
- not tracked yet
- With dependencies
- not tracked yet
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