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QTLEMM

3.1.0Package record

QTL EM Algorithm Mapping and Hotspots Detection

0packages depend
6.5Kdownloads / year
–test coverage
13/13flavors OK

Overview

About

For QTL mapping, this package comprises several functions designed to execute diverse tasks, such as simulating or analyzing data, calculating significance thresholds, and visualizing QTL mapping results. The single-QTL or multiple-QTL method, which enables the fitting and comparison of various statistical models, is employed to analyze the data for estimating QTL parameters. The models encompass linear regression, permutation tests, normal mixture models, and truncated normal mixture models. The Gaussian stochastic process is utilized to compute significance thresholds for QTL detection on a genetic linkage map within experimental populations. Two types of data, complete genotyping, and selective genotyping data from various experimental populations, including backcross, F2, recombinant inbred (RI) populations, and advanced intercrossed (AI) populations, are considered in the QTL mapping analysis. For QTL hotspot detection, statistical methods can be developed based on either utilizing individual-level data or summarized data. We have proposed a statistical framework capable of handling both individual-level data and summarized QTL data for QTL hotspot detection. Our statistical framework can overcome the underestimation of thresholds resulting from ignoring the correlation structure among traits. Additionally, it can identify different types of hotspots with minimal computational cost during the detection process. Here, we endeavor to furnish the R codes for our QTL mapping and hotspot detection methods, intended for general use in genes, genomics, and genetics studies. The QTL mapping methods for the complete and selective genotyping designs are based on the multiple interval mapping (MIM) model proposed by Kao, C.-H. , Z.-B. Zeng and R. D. Teasdale (1999) <doi: 10.1534/genetics.103.021642> and H.-I Lee, H.-A. Ho and C.-H. Kao (2014) <doi: 10.1534/genetics.114.168385>, respectively. The QTL hotspot detection analysis is based on the method by Wu, P.-Y., M.-.H. Yang, and C.-H. Kao (2021) <doi: 10.1093/g3journal/jkab056>.

Install

Health

CRAN checks
13OK
Slowest check: 2.2 min · r-oldrel-windows-x86_64
Status changes
  • OK13 OK2026-09-08
  • ERROR12 OK, 1 ERROR2026-09-07
  • OK13 OK2026-08-05
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK14 OK2026-03-10
Advisories

none known

Documentation

In release 3.1.0
READMENoVignettesNoNEWSNoCitation fileNoWebsitenot declared in DESCRIPTION
Help pages
14
Examples that run
100%14 run in a plain check
Exported functions with examples
100%
Documented parameters
100%
Return-value docs
100%
Help pages citing references
100%

Downloads

6.5K
CRAN downloads in the past year
Rank #6,996 · ~18/day · ~545/mo
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45630 days
1.3K90 days
6.5K1 year
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Repository

0Stars
0Forks
0Open issues
0Open PRs
1Releases
60Commits
1Commit identities
60 commits · Last activity 2025-09-16
Responsiveness
not measured

Releases over time

2024-03-18 · 12026-07-07 · 1
PracticesBeta

Checks run against github.com/py-chung/qtlemm on 2026-10-25.

No development-tooling practices detected in the upstream repository.

How this is detected·Detection ruleset v4 (2026-10-20)

Dependencies

Declared dependencies
2 external dependencies (excludes base and recommended)

Installing QTLEMM adds 2 packages (2 with compiled code, 1.2 MB of source tarballs). Heaviest: mvtnorm 1.0 MB, gtools 236 KB.

Depends (0)
none
Imports (6)
mvtnormutilsstatsgraphicsgrDevicesgtools
LinkingTo (0)
none
Suggests (0)
none
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Datasets

People & History

People (8)
Maintainer since 0.1.0 (2021)
Author · added in 1.3.0
Author · added in 1.3.0
Author · added in 1.3.0
Author · added in 1.3.0
Author · added in 1.3.0
Author · added in 1.3.0
Releases (20)

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Package metadata

First published
2021-06-11
Total releases
20 / 5 yrs
License
GPL-2 OSI
Download size
1.9 MB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("QTLEMM")
Chung, P., Guo, Y. -., Ho, H. -., Kao, C., Lee, H. -., Wu, P. -., Yang, M. -., & Zeng, M. -. (2025). QTLEMM: QTL EM Algorithm Mapping and Hotspots Detection (Version 3.1.0) [Computer software]. https://doi.org/10.32614/CRAN.package.QTLEMM

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for QTLEMM version 3.1.0 [Data set]. HJJB, LLC. Data release v2026-10-26. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-26, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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