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PathwayVote

0.1.3

Robust Pathway Enrichment for DNA Methylation Studies Using Ensemble Voting

0packages depend
2.1Kdownloads / year
test coverage
13/13checks pass

Overview

About
Maintained by Yinan ZhengFirst published 2025-04-164 releasesCRAN page ↗

Performs pathway enrichment analysis using a voting-based framework that integrates CpG–gene regulatory information from expression quantitative trait methylation (eQTM) data. For a grid of top-ranked CpGs and filtering thresholds, gene sets are generated and refined using an entropy-based pruning strategy that balances information richness, stability, and probe bias correction. In particular, gene lists dominated by genes with disproportionately high numbers of CpG mappings are penalized to mitigate active probe bias—a common artifact in methylation data analysis. Enrichment results across parameter combinations are then aggregated using a voting scheme, prioritizing pathways that are consistently recovered under diverse settings and robust to parameter perturbations.

Install

Health

CRAN checks
13OK
Slowest check: 5.5 min · r-oldrel-windows-x86_64
Code health
None
Tests · ratio 0.00
not tracked
Coverage
100%
Documentation · exports
7
Dependencies · direct
Check history
  • OK2026-08-12
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-08-05
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • NOTE2026-08-01
    12 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-07-23
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • OK2026-07-05
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
Show 17 earlier snapshots
  • ERROR2026-07-03
    10 OK · 0 NOTE · 0 WARNING · 3 ERROR · 0 FAILURE
  • OK2026-06-30
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-06-29
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • OK2026-06-27
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-06-21
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • OK2026-06-17
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-06-15
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • OK2026-06-09
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-06-08
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • OK2026-06-07
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-06-05
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • OK2026-05-10
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-05-03
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • OK2026-04-30
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-04-28
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • OK2026-04-25
    12 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-03-10
    12 OK · 0 NOTE · 0 WARNING · 2 ERROR · 0 FAILURE

Documentation

Documentation
READMENoVignettesNopkgdown siteNoNEWSNoCode of conductNoContributing guideNo
Examples that run
67%
Documented parameters
100%
Return-value docs
100%
References docs
0%

Downloads

2.1K
CRAN downloads in the past year
Rank #21,637 · ~6/day · ~178/mo
Daily download trend is not available in this view yet.
15730 days
51190 days
2.1K1 year
Compare downloads with other packages →
Also on128 r2u

Dependencies

Declared dependencies
10 external dependencies (excludes base and recommended)
Depends (1)
R >= 4.0.0
LinkingTo (0)
none
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Code & Tests

People & History

People (1)
Maintainer (1)
Author, Maintainer
Authors (1)
Author, Maintainer
Package Timeline

4 releases. Pick two to compare their code metrics. R releases are shown for context.

  • R
    R 4.6.0 released · 2026-04-24
  • 0.1.3Latest
    2026-01-17 · current release · diff ↗
  • 0.1.2
    2025-10-01 · diff ↗
  • 0.1.1
    2025-06-25 · diff ↗
  • 0.1.0
    2025-04-16
  • R
    R 4.5.0 released · 2025-04-11

Package metadata

First published
2025-04-16
Total releases
4 / 1 yrs
License
MIT + file LICENSE OSI
Minimum R
≥ 4.0.0
Download size
15 KB
Installed size
not tracked yet
With dependencies
not tracked yet

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("PathwayVote")
Zheng, Y. (2026). PathwayVote: Robust Pathway Enrichment for DNA Methylation Studies Using Ensemble Voting (Version 0.1.3) [Computer software]. https://doi.org/10.32614/CRAN.package.PathwayVote

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for PathwayVote version 0.1.3 [Data set]. HJJB, LLC. Data release v2026-08-22. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-22, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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