Study Design for Immunotherapy Clinical Trials
0packages depend
2Kdownloads / year
–test coverage
12/13flavors OK
Overview
About
Maintained by Bill WheelerCRAN page ↗
Perform sample size, power calculation and subsequent analysis for Immuno-oncology (IO) trials composed of responders and non-responders.
Install
Health
CRAN checks
1ERROR12OK
Check messages
ERRORexamplesr-devel-linux-x86_64-debian-gcc
Running examples in ‘PRIMEplus-Ex.R’ failed
The error most likely occurred in:
> base::assign(".ptime", proc.time(), pos = "CheckExEnv")
> ### Name: PRIMEplus.EM
> ### Title: EM algorithm
> ### Aliases: PRIMEplus.EM
> ### Keywords: EM
>
> ### ** Examples
>
> data(data, package="PRIMEplus")
> effp <- c(0.3, 0.3)
> beta0 <- c(log(0.4), log(0.6))
> ret <- PRIMEplus.EM(data, effp, beta0)
Error in a$specials[[i]] : subscript out of bounds
Calls: PRIMEplus.EM ... survfit.coxph -> model.matrix.coxph -> delete.response -> off
Execution haltedSlowest check: 2.8 min · r-devel-windows-x86_64
Status changes
- ERROR12 OK, 1 ERROR2026-10-24
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK14 OK2026-03-10
Advisories
Documentation
In release 1.0.16
READMENoVignettesNoNEWSNoCitation fileNoWebsitenot declared in DESCRIPTION
- Help pages
- 9includes a package overview page
- Examples that run
- 100%6 run in a plain check
- Exported functions with examples
- 71%
- Documented parameters
- 100%
- Return-value docs
- 100%
- Help pages citing references
- 89%
Downloads
2K
CRAN downloads in the past year
Rank #24,202 · ~5/day · ~163/mo
Daily download trend is not available in this view yet.
19530 days
51790 days
2K1 year
Also on344 r2u3 autocran
Dependencies
Declared dependencies
1 external dependency (excludes base and recommended)
Installing PRIMEplus adds 14 packages (10 with compiled code, 6.2 MB of source tarballs). Heaviest: mvtnorm 1.0 MB, vctrs 1.0 MB, msm 972 KB.
Depends (3)
R >= 3.5survivalmsm
Imports (0)
none
LinkingTo (0)
none
Suggests (0)
none
Enhances (0)
none
Code & Tests
Datasets
People & History
People (4)
Releases (1)
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- 1.0.16Latest2024-01-10 · current release
- RR 4.3.0 released · 2023-04-21
0 of 2 selectedCompare selected
Package metadata
- First published
- 2024-01-10
- Total releases
- 1 / 2 yrs
- License
- GPL-2 OSI
- Minimum R
- ≥ 3.5
- Bundled data
- 5.3 KB / 1 file
- Download size
- 28 KB
Cite
Cite this package
Run in R for the authors' preferred citation:
citation("PRIMEplus")This package has no citation file, so citation() returns this entry built from DESCRIPTION.
Cite the R Observatory
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From data release v2026-10-24, which the citation names so these numbers can be found later. More on citing and the projects behind them.