Efficient Mixed Model Analysis of Count Data in Large-Scale Genomic Sequencing Studies
Overview
An efficient tool designed for differential analysis of large-scale RNA sequencing (RNAseq) data and Bisulfite sequencing (BSseq) data in the presence of individual relatedness and population structure. 'PQLseq' first fits a Generalized Linear Mixed Model (GLMM) with adjusted covariates, predictor of interest and random effects to account for population structure and individual relatedness, and then performs Wald tests for each gene in RNAseq or site in BSseq.
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Documentation
- Help pages
- 4includes a package overview page
- Examples that run
- 100%2 run in a plain check
- Exported functions with examples
- 100%
- Documented parameters
- 100%
- Return-value docs
- 100%
- Help pages citing references
- 50%
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People & History
Maintainer since 1.2 (2020), previously Shiquan Sun (1.0 to 1.1)
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- archivedRemoved from CRAN2025-12-25issues were not addressed in time
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- 1.2.12021-06-06 · diff ↗
- RR 4.1.0 released · 2021-05-18
- unarchivedReturned to CRAN2020-05-02
- 1.22020-05-02 · diff ↗
- RR 4.0.0 released · 2020-04-24
- archivedRemoved from CRAN2020-04-18email bounced when asked for correction
- RR 3.6.0 released · 2019-04-26
- 1.12018-08-06 · diff ↗
- 1.02018-06-10
- RR 3.5.0 released · 2018-04-23
Package metadata
- First published
- 2018-06-10
- Total releases
- 4 / 8 yrs
- License
- GPL (>= 2) OSI
- Minimum R
- ≥ 2.10
- Bundled data
- 97 KB / 3 files
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