MicrobiomeSurv
0.1.0Biomarker Validation for Microbiome-Based Survival Classification and Prediction
Overview
An approach to identify microbiome biomarker for time to event data by discovering microbiome for predicting survival and classifying subjects into risk groups. Classifiers are constructed as a linear combination of important microbiome and treatment effects if necessary. Several methods were implemented to estimate the microbiome risk score such as the LASSO method by Robert Tibshirani (1998) doi:10.1002/(SICI)1097-0258(19970228)16:4%3C385::AID-SIM380%3E3.0.CO;2-3, Elastic net approach by Hui Zou and Trevor Hastie (2005) doi:10.1111/j.1467-9868.2005.00503.x, supervised principle component analysis of Wold Svante et al. (1987) doi:10.1016/0169-7439(87)80084-9, and supervised partial least squares analysis by Inge S. Helland https://www.jstor.org/stable/4616159. Sensitivity analysis on the quantile used for the classification can also be accessed to check the deviation of the classification group based on the quantile specified. Large scale cross validation can be performed in order to investigate the mostly selected microbiome and for internal validation. During the evaluation process, validation is accessed using the hazard ratios (HR) distribution of the test set and inference is mainly based on resampling and permutations technique.
Install
Health
- ERROR r-oldrel-macos-arm64
- ERROR r-oldrel-macos-x86_64
- ERROR2026-03-1011 OK · 0 NOTE · 0 WARNING · 3 ERROR · 0 FAILURE
Documentation
- Examples that run
- 86%
- Documented parameters
- not tracked
- Return-value docs
- not tracked
- References docs
- 0%
Downloads
Repository
Repository practices
1 development-tooling and community-health practice detected across 1 family in the upstream repository
Checks run against github.com/n-t-huyen/microbiomesurv on 2026-08-16.
Dependencies
Nothing depends on this yet.
Code & Tests
Datasets
People & History
1 release. R releases are shown for context.
- RR 4.6.0 released · 2026-04-24
- 0.1.0Latest2026-03-10 · current release
- RR 4.5.0 released · 2025-04-11
Package metadata
- First published
- 2023-10-12
- Total releases
- 1 / 3 yrs
- License
- GPL-3 OSI
- Minimum R
- ≥ 2.10
- Bundled data
- 231 KB / 6 files
- Download size
- 413 KB
- Installed size
- not tracked yet
- With dependencies
- not tracked yet
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