Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Proportions
Overview
Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) doi:10.1093/bioinformatics/btt459 and Kiihl et al. (2019) doi:10.1515/sagmb-2018-0031.
Install
Health
NOTECRAN incoming feasibilityr-devel-linux-x86_64-debian-clang, r-devel-linux-x86_64-debian-gcc
Maintainer: ‘Samara Kiihl <samara@ime.unicamp.br>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: c(person(given = "Samara",
family = "Kiihl",
role = c("aut", "cre"),
email = "samara@ime.unicamp.br"),
person(given = c("Maria", "Jose"),
family = "Martinez-Garrido",
role = "aut"),
person(given = "Arce",
family = "Domingo-Relloso",
role = "aut"),
person(given = "Jose",
family = "Bermudez",
role = "aut"),
person(given = "Maria",
family = "Tellez-Plaza",
role = "aut"))
as necessary.
Package CITATION file contains call(s) to old-style personList() or
as.personList(). Please use c() on person objects instead.
Package CITATION file contains call(s) to old-style citEntry(). Please
use bibentry() instead.- NOTE11 OK, 2 NOTE2026-09-08
- ERROR10 OK, 2 NOTE, 1 ERROR2026-09-07
- NOTE10 OK, 4 NOTE2026-03-10
Documentation
- Help pages
- 7
- Examples that run
- 100%1 run in a plain check
- Exported functions with examples
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- Documented parameters
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- Return-value docs
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- Help pages citing references
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- Using MLML2R HTML
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Dependencies
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Code & Tests
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- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- RR 4.1.0 released · 2021-05-18
- RR 4.0.0 released · 2020-04-24
- 0.3.3Latest
- RR 3.6.0 released · 2019-04-26
- 0.3.22019-04-06 · diff ↗
- 0.3.12018-11-12 · diff ↗
- 0.3.02018-09-30 · diff ↗
- 0.2.12018-05-17 · diff ↗
- RR 3.5.0 released · 2018-04-23
- 0.2.02018-02-21 · diff ↗
- 0.1.02018-02-13
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- RR 3.4.0 released · 2017-04-21
Package metadata
- First published
- 2018-02-13
- Total releases
- 7 / 8 yrs
- License
- MIT + file LICENSE OSI
- Bundled data
- 7.3 KB / 6 files
- Download size
- 1.2 MB
Cite
Cite this package
Run in R for the authors' entry:
citation("MLML2R")The package provides a citation file, so citation() returns the authors' own entry.
It points to 10.1515/sagmb-2018-0031.
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From data release v2026-10-21, which the citation names so these numbers can be found later. More on citing and the projects behind them.