MLML2R
Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Proportions
Description
Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) <doi:10.1093/bioinformatics/btt459> and Kiihl et al. (2019) <doi:10.1515/sagmb-2018-0031>.
Downloads
239
Last 30 days
18869th
595
Last 90 days
2.4K
Last year
Trend: +45.7% (30d vs prior 30d)
CRAN Check Status
Show all 14 flavors
| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | NOTE |
| r-devel-linux-x86_64-debian-gcc | NOTE |
| r-devel-linux-x86_64-fedora-clang | OK |
| r-devel-linux-x86_64-fedora-gcc | OK |
| r-devel-macos-arm64 | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | NOTE |
| r-oldrel-macos-x86_64 | NOTE |
| r-oldrel-windows-x86_64 | OK |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
| r-release-macos-x86_64 | OK |
| r-release-windows-x86_64 | OK |
Check details (4 non-OK)
CRAN incoming feasibility
Maintainer: ‘Samara Kiihl <samara@ime.unicamp.br>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: c(person(given = "Samara",
family = "Kiihl",
role = c("aut", "cre"),
email = "samara@ime.unicamp.br"),
person(given = c("Maria", "Jose"),
family = "Martinez-Garrido",
role = "aut"),
person(given = "Arce",
family = "Domingo-Relloso",
role = "aut"),
person(given = "Jose",
family = "Bermudez",
role = "aut"),
person(given = "Maria",
family = "Tellez-Plaza",
role = "aut"))
as necessary.
Package CITATION file contains call(s) to old-style personList() or
as.personList(). Please use c() on person objects instead.
Package CITATION file contains call(s) to old-style citEntry(). Please
use bibentry() instead.
CRAN incoming feasibility
Maintainer: ‘Samara Kiihl <samara@ime.unicamp.br>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: c(person(given = "Samara",
family = "Kiihl",
role = c("aut", "cre"),
email = "samara@ime.unicamp.br"),
person(given = c("Maria", "Jose"),
family = "Martinez-Garrido",
role = "aut"),
person(given = "Arce",
family = "Domingo-Relloso",
role = "aut"),
person(given = "Jose",
family = "Bermudez",
role = "aut"),
person(given = "Maria",
family = "Tellez-Plaza",
role = "aut"))
as necessary.
Package CITATION file contains call(s) to old-style personList() or
as.personList(). Please use c() on person objects instead.
Package CITATION file contains call(s) to old-style citEntry(). Please
use bibentry() instead.
package dependencies
Package suggested but not available for checking: ‘IlluminaHumanMethylation450kmanifest’
package dependencies
Package suggested but not available for checking: ‘IlluminaHumanMethylation450kmanifest’
Check History
NOTE 10 OK · 4 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
CRAN incoming feasibility
Maintainer: ‘Samara Kiihl <samara@ime.unicamp.br>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: c(person(given = "Samara",
family = "Kiihl",
role = c("aut", "cre"),
...[truncated]...
e = "aut"))
as necessary.
Package CITATION file contains call(s) to old-style personList() or
as.personList(). Please use c() on person objects instead.
Package CITATION file contains call(s) to old-style citEntry(). Please
use bibentry() instead.
CRAN incoming feasibility
Maintainer: ‘Samara Kiihl <samara@ime.unicamp.br>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: c(person(given = "Samara",
family = "Kiihl",
role = c("aut", "cre"),
...[truncated]...
e = "aut"))
as necessary.
Package CITATION file contains call(s) to old-style personList() or
as.personList(). Please use c() on person objects instead.
Package CITATION file contains call(s) to old-style citEntry(). Please
use bibentry() instead.
package dependencies
Package suggested but not available for checking: ‘IlluminaHumanMethylation450kmanifest’
package dependencies
Package suggested but not available for checking: ‘IlluminaHumanMethylation450kmanifest’