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LTFHPlus

2.2.0Package record

Implementation of LT-FH++

0packages depend
3.2Kdownloads / year
16.6%test coverage
13/13flavors OK

Overview

About

Implementation of LT-FH++, an extension of the liability threshold family history (LT-FH) model. LT-FH++ uses a Gibbs sampler for sampling from the truncated multivariate normal distribution and allows for flexible family structures. LT-FH++ was first described in Pedersen, Emil M., et al. (2022) doi:10.1016/j.ajhg.2022.01.009 as an extension to LT-FH with more flexible family structures, and again as the age-dependent liability threshold (ADuLT) model Pedersen, Emil M., et al. (2023) https://www.nature.com/articles/s41467-023-41210-z as an alternative to traditional time-to-event genome-wide association studies, where family history was not considered.

Changes in 2.2.0
  • Added several functions to assist labelling relatives, summarising per-family relatives, and summary pedigree information visualisation
  • get_generations()
  • label_relatives()
  • get_relations()
  • get_family_graphs()
  • Relation_per_proband_plot()
  • Added vignette on pedigree visualisation and labelling relatives

From NEWS.md in the release

Install

Health

CRAN checks
13OK
Slowest check: 4.6 min · r-devel-windows-x86_64
Status changes
  • OK13 OK2026-09-08
  • ERROR12 OK, 1 ERROR2026-09-07
  • OK13 OK2026-08-05
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK14 OK2026-04-22
Show 2 earlier changesHide 2 earlier changes
  • ERROR13 OK, 1 ERROR2026-04-18
  • OK14 OK2026-03-10
Advisories

none known

Documentation

In release 2.2.0
READMEYes · 215 wordsVignettes· In the repository, left out of the releaseNEWSYes · 100% structured · mentions 2.2.0Citation fileNoWebsiteYes · pkgdown
Help pages
36 (1 internal)includes a package overview page
Examples that run
82%27 run in a plain check · 6 hold no code
Exported functions with examples
97%
Documented parameters
97%
Return-value docs
100%
Help pages citing references
6%

Downloads

3.2K
CRAN downloads in the past year
Rank #13,872 · ~9/day · ~264/mo
Daily download trend is not available in this view yet.
25630 days
85590 days
3.2K1 year
Compare downloads with other packages →
Also on355 r2u5 autocran

Repository

11Stars
3Forks
1Open issues
1Open PRs
7Releases
395Commits
6Commit identities
395 commits · Last activity 2025-11-17
Responsiveness
How these are sampled
PRs merged (all time)
100%
Median days to close, 50 most recently updated closed issues
8
Median days to close, 50 most recently updated closed PRs
0

Stars over time

2025-05-27 · 112026-07-07 · 11
PracticesBeta

8 development-tooling and community-health practices detected across 4 families in the upstream repository

Checks run against github.com/emilmip/ltfhplus on 2026-10-25.

Continuous integration (2)
GitHub ActionsR CMD check workflow

The R CMD check workflow runs on Linux

Docs source (4)
README.Rmdpkgdown

GitHub Pages site last deployed 2025-11-17 · The repository has a site deploy workflow

pkgdown site last built 2025-11-17

CRAN release process (1)
cran-comments.md
Lint, format, editor (1)
RStudio project
How this is detected·Detection ruleset v4 (2026-10-20)

Dependencies

Declared dependencies
20 external dependencies (excludes base and recommended)

Installing LTFHPlus adds 46 packages (26 with compiled code, 48 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, data.table 5.7 MB.

Depends (0)
none
LinkingTo (1)
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

People & History

People (6)
Author, Maintainer since 2.1.1 (2024)
Author, Thesis advisor
Contributor
Thesis advisor
Releases (5)

Pick two releases to compare their code metrics.

  • R
    R 4.6.0 released · 2026-04-24
  • 2.2.0Latest
    record
    2025-11-17 · current release · diff ↗ ·
    added 7 exports
    Relation_per_proband_plot, attach_attributes, familywise_attach_attributes, get_family_graphs, get_generations, get_relations, label_relatives
  • 2.1.4
    record
    2025-05-26 · diff ↗
  • 2.1.3
    record
    2025-05-13 · diff ↗ ·
    added 1 export
    graph_to_trio
  • R
    R 4.5.0 released · 2025-04-11
  • 2.1.2
    record
    2024-11-22 · diff ↗
  • R
    R 4.4.0 released · 2024-04-24
  • 2.1.1
    record
    2024-02-12
  • R
    R 4.3.0 released · 2023-04-21

Package metadata

First published
2024-02-12
Total releases
5 / 2 yrs
License
GPL-3 OSI
Download size
84 KB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("LTFHPlus")
Pedersen, E. M., Agerbo, E., Privé, F., Rasmussen, L., Steinbach, J., & Vilhjálmsson, B. J. (2025). LTFHPlus: Implementation of LT-FH++ (Version 2.2.0) [Computer software]. https://doi.org/10.32614/CRAN.package.LTFHPlus

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for LTFHPlus version 2.2.0 [Data set]. HJJB, LLC. Data release v2026-10-26. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-26, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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