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This package was removed from CRAN on 2024-04-20. Its history is shown below.
Reason: issues were not corrected despite reminders
Details below reflect version 1.4.9, its last release before removal.

LEANR

1.4.9

Finds "Local Subnetworks" Within an Interaction Network which Show Enrichment for Differentially Expressed Genes

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test coverage
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Overview

About
Maintained by Frederik Gwinner1 releasesCRAN page ↗

Implements the method described in "Network-based analysis of omics data: The LEAN method" [Gwinner Boulday (2016) DOI:10.1093/bioinformatics/btw676] Given a protein interaction network and a list of p-values describing a measure of interest (as e.g. differential gene expression) this method computes an enrichment p-value for the protein neighborhood of each gene and compares it to a background distribution of randomly drawn p-values. The resulting scores are corrected for multiple testing and significant hits are returned in tabular format.

Install

Health

CRAN checks

CRAN check results are not tracked yet.

Code health
Yes
Tests · ratio 0.18
not tracked
Coverage
0%
Documentation · exports
2
Dependencies · direct

Documentation

Documentation
READMEYes · 142 wordsVignettesYes · dynamicpkgdown siteNoNEWSNoCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
not tracked
Return-value docs
not tracked
References docs
27%

Downloads

Daily download trend is not available in this view yet.
Also on107 r2u17 autocran

Dependencies

Declared dependencies
7 external dependencies (excludes base and recommended)
Depends (3)
R >= 2.14igraphforeach
Imports (0)
none
LinkingTo (0)
none
Enhances (0)
none
Reverse dependencies
0direct
indirect (not tracked)

Nothing depends on this yet.

Code & Tests

Datasets

People & History

People (1)
Other (1)
Contributor
Package Timeline

1 release. R releases are shown for context.

  • R
    R 4.4.0 released · 2024-04-24
  • archivedRemoved from CRAN
    2024-04-20
    issues were not corrected despite reminders
  • R
    R 4.3.0 released · 2023-04-21
  • R
    R 4.2.0 released · 2022-04-22
  • R
    R 4.1.0 released · 2021-05-18
  • R
    R 4.0.0 released · 2020-04-24
  • R
    R 3.6.0 released · 2019-04-26
  • R
    R 3.5.0 released · 2018-04-23
  • R
    R 3.4.0 released · 2017-04-21
  • 1.4.9
    2016-11-12
  • R
    R 3.3.0 released · 2016-05-03

Package metadata

Total releases
1
License
GPL-3 OSI
Minimum R
≥ 2.14
Bundled data
1.4 MB / 7 files
Download size
not tracked yet
Installed size
not tracked yet
With dependencies
not tracked yet

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("LEANR")
Gwinner, F. (n.d.). LEANR: Finds "Local Subnetworks" Within an Interaction Network which Show Enrichment for Differentially Expressed Genes (Version 1.4.9) [Computer software]. Retrieved August 13, 2026, from https://CRAN.R-project.org/package=LEANR

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for LEANR version 1.4.9 [Data set]. HJJB, LLC. Data release v2026-08-11. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-11, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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