Identification of Cancer Dysfunctional Subpathway with Omics Data
Overview
Identify Cancer Dysfunctional Sub-pathway by integrating gene expression, DNA methylation and copy number variation, and pathway topological information. 1)We firstly calculate the gene risk scores by integrating three kinds of data: DNA methylation, copy number variation, and gene expression. 2)Secondly, we perform a greedy search algorithm to identify the key dysfunctional sub-pathways within the pathways for which the discriminative scores were locally maximal. 3)Finally, the permutation test was used to calculate statistical significance level for these key dysfunctional sub-pathways.
Install
Health
CRAN check results are not tracked yet.
Documentation
- Help pages
- 13includes a package overview page
- Examples that run
- 100%10 run in a plain check
- Exported functions with examples
- 91%
- Documented parameters
- 100%
- Return-value docs
- 91%
- Help pages citing references
- 8%
Downloads
Dependencies
Code & Tests
Datasets
People & History
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- archivedRemoved from CRAN2026-02-21issues were not corrected despite reminders
- RR 4.5.0 released · 2025-04-11
- 0.1.32024-08-01 · diff ↗
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- unarchivedReturned to CRAN2021-07-15
- 0.1.22021-07-15 · diff ↗
- archivedRemoved from CRAN2021-05-22policy violation on Internet access
- RR 4.1.0 released · 2021-05-18
- RR 4.0.0 released · 2020-04-24
- RR 3.6.0 released · 2019-04-26
- 0.1.12019-01-25
- RR 3.5.0 released · 2018-04-23
Package metadata
- First published
- 2019-01-25
- Total releases
- 3 / 7 yrs
- License
- GPL (>= 2) OSI
- Minimum R
- ≥ 4.3.0
- Bundled data
- 322 KB / 1 file
Cite
Cite this package
Run in R for the authors' entry:
citation("ICDS")The package provides a citation file, so citation() returns the authors' own entry.
It points to 10.3389/fgene.2019.00441.
Cite the R Observatory
For a number measured here: a download total, a coverage figure, an archival date.
From data release v2026-10-23, which the citation names so these numbers can be found later. More on citing and the projects behind them.