HDStIM

Description

A method for identifying responses to experimental stimulation in mass or flow cytometry that uses high dimensional analysis of measured parameters and can be performed with an end-to-end unsupervised approach. In the context of in vitro stimulation assays where high-parameter cytometry was used to monitor intracellular response markers, using cell populations annotated either through automated clustering or manual gating for a combined set of stimulated and unstimulated samples, 'HDStIM' labels cells as responding or non-responding. The package also provides auxiliary functions to rank intracellular markers based on their contribution to identifying responses and generating diagnostic plots.

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See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
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R Observatory began tracking this package on Mar 10, 2026; it first appeared on CRAN Jun 24, 2022. Releases before tracking aren’t shown.