Comprehensive Analysis of 'GENCODE' Annotations and Splice Site Motifs
Overview
A comprehensive suite of helper functions designed to facilitate the analysis of genomic annotations from the 'GENCODE' database https://www.gencodegenes.org/, supporting both human and mouse genomes. This toolkit enables users to extract, filter, and analyze a wide range of annotation features including genes, transcripts, exons, and introns across different 'GENCODE' releases. It provides functionality for cross-version comparisons, allowing researchers to systematically track annotation updates, structural changes, and feature-level differences between releases. In addition, the package can generate high-quality FASTA files containing donor and acceptor splice site motifs, which are formatted for direct input into the 'MaxEntScan' tool (Yeo and Burge, 2004 doi:10.1089/1066527041410418), enabling accurate calculation of splice site strength scores.
Bug fixes
- Added missing global variable declaration to fix dplyr update (PR #04, thanks @DavisVaughan).
From NEWS.md in the release
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-06-09
- ERROR12 OK, 1 ERROR2026-06-08
- OK13 OK2026-05-10
Show 3 earlier changesHide 3 earlier changes
- ERROR12 OK, 1 ERROR2026-05-03
- OK12 OK2026-04-25
- ERROR12 OK, 1 NOTE, 1 ERROR2026-03-10
Documentation
- Help pages
- 19
- Examples that run
- 58%11 run in a plain check · 8 never run
- Exported functions with examples
- 100%
- Documented parameters
- 100%
- Return-value docs
- 100%
- Help pages citing references
- 0%
Downloads
Repository
- PRs merged (all time)
- 100%
- Median days to close, 50 most recently updated closed issues
- 12
- Median days to close, 50 most recently updated closed PRs
- 4
Stars over time
Forks over time
Releases over time
Issues over time
PRs over time
6 development-tooling and community-health practices detected across 3 families in the upstream repository
Checks run against github.com/monahton/gencodymo2 on 2026-10-11.
GitHub Pages site last deployed 2026-02-05 · The repository has a site deploy workflow
pkgdown site last built 2026-02-05
Dependencies
Installing GencoDymo2 adds 28 packages (15 with compiled code, 25 MB of source tarballs). Heaviest: stringi 11 MB, data.table 5.7 MB, vctrs 1.0 MB. 5 more not on CRAN are not measured.
Code & Tests
People & History
Package metadata
- First published
- 2025-05-15
- Total releases
- 4 / 1 yrs
- License
- GPL (>= 3) OSI
- Download size
- 462 KB
Cite
Cite this package
Run in R for the authors' entry:
citation("GencoDymo2")The package provides a citation file, so citation() returns the authors' own entry.
It points to 10.3389/fgene.2020.00488, 10.5281/zenodo.15302316.
Cite the R Observatory
For a number measured here: a download total, a coverage figure, an archival date.
From data release v2026-10-18, which the citation names so these numbers can be found later. More on citing and the projects behind them.