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GRAB

0.2.5

Genome-Wide Robust Analysis for Biobank Data (GRAB)

0packages depend
4.7Kdownloads / year
test coverage
13/13checks pass

Overview

About
Maintained by Woody MiaoFirst published 2025-07-255 releasesCRAN page ↗

Provides a comprehensive suite of genome-wide association study (GWAS) methods specifically designed for biobank-scale data, including but not limited to, robust approaches for time-to-event traits (Li et al., 2025 doi:10.1038/s43588-025-00864-z) and ordinal categorical traits (Bi et al., 2021 doi:10.1016/j.ajhg.2021.03.019). The package also offers general frameworks for GWAS of any trait type (Bi et al., 2020 doi:10.1016/j.ajhg.2020.06.003), while accounting for sample relatedness (Xu et al., 2025 doi:10.1038/s41467-025-56669-1) or population structure (Ma et al., 2025 doi:10.1186/s13059-025-03827-9). By accurately approximating score statistic distributions using saddlepoint approximation (SPA), these methods can effectively control type I error rates for rare variants and in the presence of unbalanced phenotype distributions. Additionally, the package includes functions for simulating genotype and phenotype data to support research and method development.

Install

Health

CRAN checks
13OK
Slowest check: 7.1 min · r-devel-windows-x86_64
Code health
None
Tests · ratio 0.00
not tracked
Coverage
100%
Documentation · exports
12
Dependencies · direct
Check history
  • OK2026-08-05
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • NOTE2026-08-01
    12 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • OK2026-06-09
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-06-08
    12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • OK2026-05-02
    13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
Show 3 earlier snapshots
  • NOTE2026-04-22
    12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
  • ERROR2026-04-18
    11 OK · 2 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
  • NOTE2026-03-10
    12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

Documentation
READMEYes · 135 wordsVignettesNopkgdown siteNoNEWSNoCode of conductNoContributing guideNo
Examples that run
100%
Documented parameters
88%
Return-value docs
100%
References docs
25%

Downloads

4.7K
CRAN downloads in the past year
Rank #7,924 · ~13/day · ~395/mo
Daily download trend is not available in this view yet.
31230 days
1.1K90 days
4.7K1 year
Compare downloads with other packages →
Also on435 r2u3K conda_forge

Dependencies

Declared dependencies
18 external dependencies (excludes base and recommended)
Depends (1)
R >= 3.5.0
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Code & Tests

Datasets

People & History

People (6)
Maintainer (1)
Maintainer
Authors (5)
Author
Package Timeline

5 releases. Pick two to compare their code metrics. R releases are shown for context.

  • 0.2.5Latest
    2026-07-03 · current release · diff ↗
  • R
    R 4.6.0 released · 2026-04-24
  • 0.2.4
    2025-12-05 · diff ↗
  • 0.2.3
    2025-08-20 · diff ↗
  • 0.2.2
    2025-07-29 · diff ↗
  • 0.2.1
    2025-07-25
  • R
    R 4.5.0 released · 2025-04-11

Package metadata

First published
2025-07-25
Total releases
5 / 1 yrs
License
GPL (>= 2) OSI
Minimum R
≥ 3.5.0
Download size
1.7 MB
Installed size
not tracked yet
With dependencies
not tracked yet

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("GRAB")
Miao, W., Bi, W., Dey, R., Lee, S., Zhao, Z., & Zhou, W. (2026). GRAB: Genome-Wide Robust Analysis for Biobank Data (GRAB) (Version 0.2.5) [Computer software]. https://doi.org/10.32614/CRAN.package.GRAB

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for GRAB version 0.2.5 [Data set]. HJJB, LLC. Data release v2026-08-24. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-24, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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