Family Age-at-Onset Data Simulation and Penetrance Estimation
Overview
Simulates age-at-onset traits associated with a segregating major gene in family data obtained from population-based, clinic-based, or multi-stage designs. Appropriate ascertainment correction is utilized to estimate age-dependent penetrance functions either parametrically from the fitted model or nonparametrically from the data. The Expectation and Maximization algorithm can infer missing genotypes and carrier probabilities estimated from family's genotype and phenotype information or from fitted models. Plot functions include pedigrees of simulated families and predicted penetrance curves based on specified parameter values. For more information see Choi, Y.-H., Briollais, L., He, W. and Kopciuk, K. (2021) FamEvent: An R Package for Generating and Modeling Time-to-Event Data in Family Designs, Journal of Statistical Software 97 (7), 1-30.
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-05-20
- NOTE11 OK, 2 NOTE2026-05-10
- WARNING11 OK, 1 NOTE, 1 WARNING2026-05-09
Show 1 earlier changeHide 1 earlier change
- NOTE12 OK, 2 NOTE2026-03-10
Documentation
- Help pages
- 31includes a package overview page
- Examples that run
- 78%21 run in a plain check · 6 never run
- Exported functions with examples
- 86%
- Documented parameters
- 60%
- Return-value docs
- 100%
- Help pages citing references
- 32%
Downloads
Dependencies
Code & Tests
Datasets
People & History
Pick two releases to compare their code metrics.
- 3.3Latest
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- 3.2
- RR 4.4.0 released · 2024-04-24
- unarchivedReturned to CRAN2024-04-04
- 3.12024-04-04 · diff ↗ ·
removed 10 exports
simfam_c, summary.simfam_c, plot.simfam_c, penplot_c, penmodel_c, print.penmodel_c, print.summary.penmodel_c, penetrance_c, summary.penmodel_c, plot.penmodel_cadded 12 exports
simfam2, summary.simfam2, simfam_cmp, summary.simfam_cmp, plot.simfam_cmp, penplot_cmp, penmodel_cmp, print.penmodel_cmp, print.summary.penmodel_cmp, penetrance_cmp, summary.penmodel_cmp, plot.penmodel_cmp - archivedRemoved from CRAN2024-03-01issues were not corrected in time
- RR 4.3.0 released · 2023-04-21
- unarchivedReturned to CRAN2022-11-17
- 3.02022-11-17 · diff ↗ ·
added 10 exports
simfam_c, summary.simfam_c, plot.simfam_c, penplot_c, penmodel_c, print.penmodel_c, print.summary.penmodel_c, penetrance_c, summary.penmodel_c, plot.penmodel_c - archivedRemoved from CRAN2022-07-21check problems were not corrected despite reminders
- RR 4.2.0 released · 2022-04-22
- RR 4.1.0 released · 2021-05-18
- 2.12021-03-17 · diff ↗
- RR 4.0.0 released · 2020-04-24
Show 10 earlier eventsHide 10 earlier events
- RR 3.6.0 released · 2019-04-26
- 2.0
- RR 3.5.0 released · 2018-04-23
- RR 3.4.0 released · 2017-04-21
- 1.3
- 1.2
- RR 3.3.0 released · 2016-05-03
- 1.12016-03-09 · diff ↗
- 1.02016-02-09
- RR 3.2.0 released · 2015-04-16
Package metadata
- First published
- 2016-02-09
- Total releases
- 10 / 10 yrs
- License
- GPL (>= 2) OSI
- Minimum R
- ≥ 3.3.0
- Bundled data
- 6.5 KB / 1 file
- Download size
- 114 KB
Cite
Cite this package
Run in R for the authors' entry:
citation("FamEvent")The package provides a citation file, so citation() returns the authors' own entry.
Cite the R Observatory
For a number measured here: a download total, a coverage figure, an archival date.
From data release v2026-10-22, which the citation names so these numbers can be found later. More on citing and the projects behind them.