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DoseFinding

Planning and Analyzing Dose Finding Experiments

v1.4-1 · Jul 9, 2025 · GPL-3

Description

The DoseFinding package provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting non-linear dose-response models (using Bayesian and non-Bayesian estimation), calculating optimal designs and an implementation of the MCPMod methodology (Pinheiro et al. (2014) <doi:10.1002/sim.6052>).

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CRAN Check Status

14 OK
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r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK

Check History

OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026

Reverse Dependencies (11)

Dependency Network

Dependencies Reverse dependencies ggplot2 lattice mvtnorm MCPModGeneral TestingSimilarity BayesianMCPMod MCPModBC RLoptimal clinDR dosedesignR uniReg MCPModPack TrialSimulator multcomp DoseFinding

Version History

new 1.4-1 Mar 10, 2026
updated 1.4-1 ← 1.3-1 diff Jul 8, 2025
updated 1.3-1 ← 1.2-1 diff Mar 10, 2025
updated 1.2-1 ← 1.1-1 diff Aug 22, 2024
updated 1.1-1 ← 1.0-5 diff Nov 1, 2023
updated 1.0-5 ← 1.0-4 diff Jun 26, 2023
updated 1.0-4 ← 1.0-3 diff May 17, 2023
updated 1.0-3 ← 1.0-2 diff Jan 5, 2023
updated 1.0-2 ← 1.0-1 diff Oct 2, 2021
updated 1.0-1 ← 0.9-17 diff Jun 24, 2021
updated 0.9-17 ← 0.9-16 diff Nov 15, 2019
updated 0.9-16 ← 0.9-15 diff Jan 3, 2018
updated 0.9-15 ← 0.9-14 diff Jul 26, 2016
updated 0.9-14 ← 0.9-13 diff Feb 2, 2016
updated 0.9-13 ← 0.9-12 diff Nov 10, 2015
updated 0.9-12 ← 0.9-11 diff Sep 27, 2014
updated 0.9-11 ← 0.9-10 diff Feb 10, 2014
updated 0.9-10 ← 0.9-9 diff Nov 24, 2013
updated 0.9-9 ← 0.9-8 diff Oct 15, 2013
updated 0.9-8 ← 0.9-7 diff Sep 17, 2013